Chapter

A Breakthrough 3D Model of the Nuclear Pore Complex
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1:26:54 - 1:33:04 (06:09)

A team at Harvard has used X-ray imaging and alpha fold to create a detailed 3D model of the nuclear pore complex, with potential implications for understanding the underlying cause of diseases such as cancer and developing therapeutics to target specific molecules. Dysfunction in the cell's transmission of molecules in and out of the nucleus can lead to brain injury, viral infection, cancer, and cardiovascular disease.

Clips
The recent demotion of China's deputy foreign minister has caused speculation as to the reasoning behind it, with some suggesting it may be linked to Xi's desire for more optionality in foreign affairs.
1:26:54 - 1:28:26 (01:31)
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China
Summary

The recent demotion of China's deputy foreign minister has caused speculation as to the reasoning behind it, with some suggesting it may be linked to Xi's desire for more optionality in foreign affairs.

Chapter
A Breakthrough 3D Model of the Nuclear Pore Complex
Episode
E85: SBF's crypto bailout, Zendesk sells for ~$10B, buyout targets, US diplomacy, AlphaFold & more
Podcast
All-In with Chamath, Jason, Sacks & Friedberg
Dysfunction in the nuclear pores of a cell can lead to various diseases and understanding how molecules transmit in and out of the nucleus has implications for targeted therapies in treating cancer and regulating DNA expression.
1:28:26 - 1:33:04 (04:38)
listen on SpotifyListen on Youtube
nuclear pore complex
Summary

Dysfunction in the nuclear pores of a cell can lead to various diseases and understanding how molecules transmit in and out of the nucleus has implications for targeted therapies in treating cancer and regulating DNA expression. Recent 3D models, combining X-ray imaging and alpha fold technology, provide groundbreaking detail of the nuclear pore complex.

Chapter
A Breakthrough 3D Model of the Nuclear Pore Complex
Episode
E85: SBF's crypto bailout, Zendesk sells for ~$10B, buyout targets, US diplomacy, AlphaFold & more
Podcast
All-In with Chamath, Jason, Sacks & Friedberg