Chapter
Barriers to Epigenetic Inheritance
39:37 - 55:58 (16:20)
Epigenetic reprogramming is one of the two main barriers to epigenetic inheritance, where chemical changes and modifications acquired by cells are mostly erased in the transition between generations. However, some examples of imprinted genes show that epigenetic inheritance is possible based on maintenance of chemical modifications across generations.
Clips
Epigenetic reprogramming and chemical modifications are the two main barriers to inheritance of acquired traits.
39:37 - 45:49 (06:12)
Summary
Epigenetic reprogramming and chemical modifications are the two main barriers to inheritance of acquired traits. Epigenetics is not just limited to modifications of DNA, but also the interaction between genes and their products that brings about the phenotype.
ChapterBarriers to Epigenetic Inheritance
EpisodeDr. Oded Rechavi: Genes & the Inheritance of Memories Across Generations
PodcastHuberman Lab
This podcast episode explores how epigenetic inheritance, which affects the way certain genes are used without changing the DNA sequence, can impact the expression and reproduction of cells and organs in human beings.
45:49 - 51:11 (05:22)
Summary
This podcast episode explores how epigenetic inheritance, which affects the way certain genes are used without changing the DNA sequence, can impact the expression and reproduction of cells and organs in human beings.
ChapterBarriers to Epigenetic Inheritance
EpisodeDr. Oded Rechavi: Genes & the Inheritance of Memories Across Generations
PodcastHuberman Lab
The concept of epigenetic inheritance has been explored through numerous epidemiological studies in humans and animal models, which have identified that the environment of the parents somehow changes the children's characteristics.
51:11 - 55:58 (04:46)
Summary
The concept of epigenetic inheritance has been explored through numerous epidemiological studies in humans and animal models, which have identified that the environment of the parents somehow changes the children's characteristics. But the mechanisms behind it remain largely unknown, and there are two main barriers to understanding it better: the difficulty of separating nature from nurture and the fact that the mechanism is not fully understood.