Chapter
Can Ketamine and Creatine Help Depression?
1:17:16 - 1:28:32 (11:15)
Ketamine and PCP, drugs that affect the NMDA receptor, have been shown to improve mood and possibly help with the treatment of depression. Creatine may also have a role in improving mood and supporting other treatments for depression.
Clips
The creatine system has a logical biochemical pathway to support the finding that it improves mood and can offset the effects of major depression in some cases, or improve the effects of antidepressant medication in many cases by increasing the activity of the forebrain phosphocreatine system, which leads to changes in the way the NMDA receptors function.
1:17:16 - 1:22:56 (05:40)
Summary
The creatine system has a logical biochemical pathway to support the finding that it improves mood and can offset the effects of major depression in some cases, or improve the effects of antidepressant medication in many cases by increasing the activity of the forebrain phosphocreatine system, which leads to changes in the way the NMDA receptors function.
ChapterCan Ketamine and Creatine Help Depression?
EpisodeUnderstanding & Conquering Depression
PodcastHuberman Lab
Ketamine has been proven to provide relief from depression for some people.
1:22:56 - 1:26:41 (03:44)
Summary
Ketamine has been proven to provide relief from depression for some people. Although it is still considered experimental, it can legally be used for treatment with a psychiatrist in certain contexts.
ChapterCan Ketamine and Creatine Help Depression?
EpisodeUnderstanding & Conquering Depression
PodcastHuberman Lab
Layer five activity in the cortex may be important for rewiring the brain in certain ways, including the alleviation of major depression symptoms with emerging treatments like psilocybin and NMDA receptor blockers.
1:26:41 - 1:28:32 (01:51)
Summary
Layer five activity in the cortex may be important for rewiring the brain in certain ways, including the alleviation of major depression symptoms with emerging treatments like psilocybin and NMDA receptor blockers.