Chapter
Cell-free DNA for Early Cancer Detection
10:38 - 15:50 (05:12)
The use of cell-free DNA from broken down cells, such as red blood cells or monocytes, can detect cancer with high specificity and positive predictive value, despite the small amount of DNA captured, making it a promising early detection method.
Clips
Cell free DNA are small fragments of DNA released spontaneously by cells which can be used for early detection of cancer even in people who do not display any symptoms of the disease.
10:38 - 12:04 (01:25)
Summary
Cell free DNA are small fragments of DNA released spontaneously by cells which can be used for early detection of cancer even in people who do not display any symptoms of the disease. Using this method "like looking at meteor fragments...being able to understand what type of an asteroid they came from."
ChapterCell-free DNA for Early Cancer Detection
Episode#517: Dr. Peter Attia on Longevity Drugs, Alzheimer's Disease, and the 3 Most Important Levers to Pull
PodcastThe Tim Ferriss Show
A medical test with a modest sensitivity of 50% and a high specificity can produce incredible positive and negative predictive values, which can determine the probability of having or not having a certain condition based on the test results and pretest probability.
12:04 - 15:50 (03:46)
Summary
A medical test with a modest sensitivity of 50% and a high specificity can produce incredible positive and negative predictive values, which can determine the probability of having or not having a certain condition based on the test results and pretest probability.