This episode discusses the critical time-sensitive nature of bipolar disorder and the urgency of getting effective treatments early in order to prevent some of the longer lasting neural circuit changes. Ketamine has shown to be a very effective treatment for major depression and the major depressive episodes of people that suffer from bipolar depression.
Homeostatic plasticity is a type of neuroplasticity that involves changes in the number of receptors in the postsynaptic neuron in response to changes in neural activity. This can lead to overall circuits becoming more or less excitable.
This podcast episode discusses alternative therapeutic options for those suffering from bipolar disorder beyond typical medications and the importance of avoiding ineffective treatments in order to combat the disorder more successfully.