Chapter

Investigating the Role of Nucleus Accumbens in Anorexia and Obesity
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1:13:25 - 1:21:27 (08:01)

The nucleus accumbens may be a site that harbors cells responsible for craving and fasting states, leading to compulsive overeating or undereating, which are similar features in both anorexia and obesity phenotypes. Investigating this may help us understand more about how the brain works, as structures do not control functions entirely.

Clips
This episode explores how the brain processes rewards and how the nucleus accumbens is involved in craving not just positive rewards, but a fasted state as well, possibly even contributing to anorexia.
1:13:25 - 1:16:57 (03:31)
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Neuroscience
Summary

This episode explores how the brain processes rewards and how the nucleus accumbens is involved in craving not just positive rewards, but a fasted state as well, possibly even contributing to anorexia.

Chapter
Investigating the Role of Nucleus Accumbens in Anorexia and Obesity
Episode
Dr. Casey Halpern: Biology & Treatments for Compulsive Behaviors & Binge Eating
Podcast
Huberman Lab
Patients with obesity who have a compulsion towards food are more similar to anorexics than different.
1:16:57 - 1:19:22 (02:24)
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Obesity, Anorexia
Summary

Patients with obesity who have a compulsion towards food are more similar to anorexics than different. The two conditions are both phenotypes resulting from a compulsion to either overeat or under eat despite the risk, and can be tackled using similar approaches.

Chapter
Investigating the Role of Nucleus Accumbens in Anorexia and Obesity
Episode
Dr. Casey Halpern: Biology & Treatments for Compulsive Behaviors & Binge Eating
Podcast
Huberman Lab
The nucleus accumbens seems to be related to the compulsion to withhold from eating, and stimulation in this area has been explored in the treatment of anorexia.
1:19:22 - 1:21:27 (02:05)
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Anorexia
Summary

The nucleus accumbens seems to be related to the compulsion to withhold from eating, and stimulation in this area has been explored in the treatment of anorexia. Studies have examined the effects of deep brain stimulation targeting the nucleus accumbens, as well as the indirect effects of targeting area 25 which is directly connected.

Chapter
Investigating the Role of Nucleus Accumbens in Anorexia and Obesity
Episode
Dr. Casey Halpern: Biology & Treatments for Compulsive Behaviors & Binge Eating
Podcast
Huberman Lab