Chapter

Measuring Lithosterol and Desmosterol for Cholesterol Synthesis
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1:41:35 - 1:47:28 (05:53)

Experts suggest that high desmosterol levels may indicate cholesterol overproduction in the body. An enzyme inhibitor drug that served as the first medication for hypercholesterolemia treatment also targets the same enzyme related to cholesterol synthesis.

Clips
Measuring lithosterol and desmosterol helps determine the amount of cholesterol being synthesized by the body.
1:41:35 - 1:44:19 (02:43)
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Lipids
Summary

Measuring lithosterol and desmosterol helps determine the amount of cholesterol being synthesized by the body. The first-ever drug approved to treat hypercholesterolemia targeted the same enzyme that inhibits the process of turning desmosterol into cholesterol.

Chapter
Measuring Lithosterol and Desmosterol for Cholesterol Synthesis
Episode
Dr. Peter Attia: Exercise, Nutrition, Hormones for Vitality & Longevity
Podcast
Huberman Lab
Desmosterol has been shown to have potential toxicity to the testes at high doses in rodent studies, while lower doses may increase luteinizing hormone and may not be a good thing for the body.
1:44:19 - 1:47:28 (03:09)
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Desmosterol
Summary

Desmosterol has been shown to have potential toxicity to the testes at high doses in rodent studies, while lower doses may increase luteinizing hormone and may not be a good thing for the body. Pre and post blood work has shown an increase in luteinizing hormone in individuals taking desmosterol.

Chapter
Measuring Lithosterol and Desmosterol for Cholesterol Synthesis
Episode
Dr. Peter Attia: Exercise, Nutrition, Hormones for Vitality & Longevity
Podcast
Huberman Lab