Chapter
Metformin as a potential treatment for breast cancer
1:00:35 - 1:02:53 (02:18)
Metformin, a drug commonly used to lower glucose and insulin levels, has been explored as a potential treatment for breast cancer.
Clips
The randomized controlled trials on Metformin are looking at non-hard outcomes, making it difficult to infer causality as the hazard ratios are low.
1:00:35 - 1:01:23 (00:48)
Summary
The randomized controlled trials on Metformin are looking at non-hard outcomes, making it difficult to infer causality as the hazard ratios are low. The studies are conducted on women who are newly diagnosed with breast cancer, in a neoadjuvant therapy window.
ChapterMetformin as a potential treatment for breast cancer
Episode#193: My Life Extension Pilgrimage to Easter Island
PodcastThe Tim Ferriss Show
Studies have tried to determine whether Metformin directly inhibits the mitochondria in a patient's body or whether the medication indirectly inhibits glucose excretion which leads to lower insulin, glucose and IGF1 levels in the blood.
1:01:23 - 1:02:05 (00:42)
Summary
Studies have tried to determine whether Metformin directly inhibits the mitochondria in a patient's body or whether the medication indirectly inhibits glucose excretion which leads to lower insulin, glucose and IGF1 levels in the blood.
ChapterMetformin as a potential treatment for breast cancer
Episode#193: My Life Extension Pilgrimage to Easter Island
PodcastThe Tim Ferriss Show
Researchers discuss the differing ways in which Metformin and Rapamycin affect cancer cells and the body's glucose and insulin levels, as well as the long-standing research on rapamycin's ability to inhibit mTOR.
1:02:05 - 1:02:53 (00:48)
Summary
Researchers discuss the differing ways in which Metformin and Rapamycin affect cancer cells and the body's glucose and insulin levels, as well as the long-standing research on rapamycin's ability to inhibit mTOR.