Chapter

Neuronal Circuitry behind Aggression and Fear in the Brain
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43:09 - 51:19 (08:09)

Discussion on the role of aggression-promoting neurons in the brain and their relation to fear neurons and mental illnesses. Progesterone and estrogen are also shown to play a role in aggression in mice.

Clips
The fear and aggression neurons in the brain have many overlapping regions they project to, which raises the question of why mental illnesses based on maladaptations of fear are more acceptable than those based on maladaptive aggression.
43:09 - 47:38 (04:28)
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Neuroscience
Summary

The fear and aggression neurons in the brain have many overlapping regions they project to, which raises the question of why mental illnesses based on maladaptations of fear are more acceptable than those based on maladaptive aggression. Activation of the fear neurons leads to an arousal process and the VMH projects to about 30 different regions in the brain, integrating information from various sensory modalities into a low-dimensional pressure to attack representation.

Chapter
Neuronal Circuitry behind Aggression and Fear in the Brain
Episode
Dr. David Anderson: The Biology of Aggression, Mating, & Arousal
Podcast
Huberman Lab
Research suggests that estrogen, testosterone, and progesterone all play a role in aggression, with studies showing that both estrogen and testosterone can restore aggression levels in castrated male mice.
47:38 - 51:19 (03:41)
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Hormones
Summary

Research suggests that estrogen, testosterone, and progesterone all play a role in aggression, with studies showing that both estrogen and testosterone can restore aggression levels in castrated male mice. The labeling of aggression promoting neurons in male mice with the estrogen receptor suggests its necessity for aggression.

Chapter
Neuronal Circuitry behind Aggression and Fear in the Brain
Episode
Dr. David Anderson: The Biology of Aggression, Mating, & Arousal
Podcast
Huberman Lab