Chapter

Neuropod Cells and the Gut-Brain Axis
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28:55 - 42:40 (13:45)

Neuropod neurons in the gut detect sweet foods, fatty acids, and amino acids and communicate with the brain via the vagus nerve to create the urge to seek out more of those nutrients. People have a selective preference for sweet foods even when they can't taste them, as shown by experiments with tastes infused into the gut.

Clips
Neuropod cells in the digestive tract signal to the brain about the presence of sweet foods and other types of foods, causing individuals to seek out more of those foods.
28:55 - 34:32 (05:37)
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Neuropod Cells
Summary

Neuropod cells in the digestive tract signal to the brain about the presence of sweet foods and other types of foods, causing individuals to seek out more of those foods. Studies have shown that people have a selective preference for sweet foods, even if they cannot taste them, and cutting off sweet sensing in the gut does not appear to prevent cravings for sweet foods.

Chapter
Neuropod Cells and the Gut-Brain Axis
Episode
How to Enhance Your Gut Microbiome for Brain & Overall Health
Podcast
Huberman Lab
The gut communicates with the brain through the vagus nerve, sending signals about nutrient content to release hormones such as ghrelin to stimulate food seeking behaviors.
34:32 - 39:00 (04:27)
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Gut-Brain Axis
Summary

The gut communicates with the brain through the vagus nerve, sending signals about nutrient content to release hormones such as ghrelin to stimulate food seeking behaviors. The nucleus of the solitary tract in the brain is strongly affected by these hormones and drives feeding behavior.

Chapter
Neuropod Cells and the Gut-Brain Axis
Episode
How to Enhance Your Gut Microbiome for Brain & Overall Health
Podcast
Huberman Lab
The GLP-1 pathway is a gut to brain signaling mechanism that adjusts appetite and is dependent on what an individual eats or drinks.
39:00 - 42:40 (03:40)
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GLP-1 pathway
Summary

The GLP-1 pathway is a gut to brain signaling mechanism that adjusts appetite and is dependent on what an individual eats or drinks. The pathway impacts the activity of neurons in the hypothalamus that induce feeding behaviors, and Yerba Mate consumption can tap into this pathway and suppress appetite.

Chapter
Neuropod Cells and the Gut-Brain Axis
Episode
How to Enhance Your Gut Microbiome for Brain & Overall Health
Podcast
Huberman Lab