Chapter

Potential negative effects of long-term ashwagandha use
The long-term administration of ashwagandha in rats showed negative effects on the thyroid, cortisol, and melatonin systems. While ashwagandha has potential benefits for blunting cortisol in humans, there may be negative consequences with prolonged use.
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Long-term consumption of ashwagandha may have negative effects on thyroid, cortisol and melatonin systems in humans, as shown by a study conducted on rats.
1:19:01 - 1:22:23 (03:22)
Summary
Long-term consumption of ashwagandha may have negative effects on thyroid, cortisol and melatonin systems in humans, as shown by a study conducted on rats. However, in previous episodes, we have discussed its potential benefits for some people in reducing cortisol levels to manage medium to long-term stress.