Chapter

Psychedelic Dosage Response
listen on Spotify
19:32 - 27:54 (08:22)

The author discusses the titration of dosage when taking psychedelics, comparing the effects of smoking versus intravenous ketamine, and warning against the potentially unpredictable effects of combining certain substances.

Clips
The effects of psychedelics are influenced not only by the pharmacology of the drug, but also by the individual's expectations, dose, and biochemical makeup.
19:32 - 22:46 (03:14)
listen on Spotify
psychedelics
Summary

The effects of psychedelics are influenced not only by the pharmacology of the drug, but also by the individual's expectations, dose, and biochemical makeup. Inappropriate circumstances or expectations that are not synchronized with the drug can result in no effect.

Chapter
Psychedelic Dosage Response
Episode
#592: Dennis McKenna — An Ethnopharmacologist on Hallucinogens, Sex-Crazed Cicadas, The Mushrooms of Language, BioGnosis, and Illuminating Obscure Corners
Podcast
The Tim Ferriss Show
The ability to titrate the effects of an experience in real-time is possible when using intravenous ketamine or MAO inhibitors.
22:46 - 27:54 (05:07)
listen on Spotify
Ketamine
Summary

The ability to titrate the effects of an experience in real-time is possible when using intravenous ketamine or MAO inhibitors. By gradually increasing or decreasing the dosage, users may observe the effects more efficiently.

Chapter
Psychedelic Dosage Response
Episode
#592: Dennis McKenna — An Ethnopharmacologist on Hallucinogens, Sex-Crazed Cicadas, The Mushrooms of Language, BioGnosis, and Illuminating Obscure Corners
Podcast
The Tim Ferriss Show