Chapter

Rationale behind Intermittent Dosing of Rapamycin
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43:33 - 46:51 (03:18)

The rationale behind the intermittent dosing of rapamycin is to drive catabolism. This could be done by mimicking the intermittent dosing strategy of other compounds.

Clips
In this episode, the hosts discuss the rationale behind the use of intermittent dosing of rapamycin, which was discovered to have two complexes for mTOR, known as mTOR complex one and mTORC one.
43:33 - 44:13 (00:40)
listen on Spotify
rapamycin
Summary

In this episode, the hosts discuss the rationale behind the use of intermittent dosing of rapamycin, which was discovered to have two complexes for mTOR, known as mTOR complex one and mTORC one.

Chapter
Rationale behind Intermittent Dosing of Rapamycin
Episode
#193: My Life Extension Pilgrimage to Easter Island
Podcast
The Tim Ferriss Show
Intermittent dosing of mTOR complex 1 (mTORC1) may allow for targeted inhibition without affecting mTORC2, which has been shown to have negative impacts in genetic studies.
44:13 - 44:55 (00:42)
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mTORC, intermittent dosing
Summary

Intermittent dosing of mTOR complex 1 (mTORC1) may allow for targeted inhibition without affecting mTORC2, which has been shown to have negative impacts in genetic studies. The frequency of intermittent dosing can vary and offers potential benefits that are still being researched.

Chapter
Rationale behind Intermittent Dosing of Rapamycin
Episode
#193: My Life Extension Pilgrimage to Easter Island
Podcast
The Tim Ferriss Show
This podcast discusses the complexities of treating disease with rapamycin, including the importance of dosing and inhibiting mTORC for optimal results.
44:55 - 45:31 (00:36)
listen on Spotify
Rapamycin
Summary

This podcast discusses the complexities of treating disease with rapamycin, including the importance of dosing and inhibiting mTORC for optimal results.

Chapter
Rationale behind Intermittent Dosing of Rapamycin
Episode
#193: My Life Extension Pilgrimage to Easter Island
Podcast
The Tim Ferriss Show
The speaker talks about the need to drive catabolism to promote anabolism at specific points, but also the importance of inhibiting the system and replacing bad habits with good ones.
45:31 - 46:51 (01:20)
listen on Spotify
Fitness
Summary

The speaker talks about the need to drive catabolism to promote anabolism at specific points, but also the importance of inhibiting the system and replacing bad habits with good ones.

Chapter
Rationale behind Intermittent Dosing of Rapamycin
Episode
#193: My Life Extension Pilgrimage to Easter Island
Podcast
The Tim Ferriss Show