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In this episode, the hosts discuss the rationale behind the use of intermittent dosing of rapamycin, which was discovered to have two complexes for mTOR, known as mTOR complex one and mTORC one.
43:33 - 44:13 (00:40)
Summary
In this episode, the hosts discuss the rationale behind the use of intermittent dosing of rapamycin, which was discovered to have two complexes for mTOR, known as mTOR complex one and mTORC one.
ChapterRationale behind Intermittent Dosing of Rapamycin
Episode#193: My Life Extension Pilgrimage to Easter Island
PodcastThe Tim Ferriss Show
Intermittent dosing of mTOR complex 1 (mTORC1) may allow for targeted inhibition without affecting mTORC2, which has been shown to have negative impacts in genetic studies.
44:13 - 44:55 (00:42)
Summary
Intermittent dosing of mTOR complex 1 (mTORC1) may allow for targeted inhibition without affecting mTORC2, which has been shown to have negative impacts in genetic studies. The frequency of intermittent dosing can vary and offers potential benefits that are still being researched.
ChapterRationale behind Intermittent Dosing of Rapamycin
Episode#193: My Life Extension Pilgrimage to Easter Island
PodcastThe Tim Ferriss Show
This podcast discusses the complexities of treating disease with rapamycin, including the importance of dosing and inhibiting mTORC for optimal results.
44:55 - 45:31 (00:36)
Summary
This podcast discusses the complexities of treating disease with rapamycin, including the importance of dosing and inhibiting mTORC for optimal results.
ChapterRationale behind Intermittent Dosing of Rapamycin
Episode#193: My Life Extension Pilgrimage to Easter Island
PodcastThe Tim Ferriss Show
The speaker talks about the need to drive catabolism to promote anabolism at specific points, but also the importance of inhibiting the system and replacing bad habits with good ones.
45:31 - 46:51 (01:20)
Summary
The speaker talks about the need to drive catabolism to promote anabolism at specific points, but also the importance of inhibiting the system and replacing bad habits with good ones.