Chapter
S-ketamine versus R-ketamine
2:56:30 - 3:03:53 (07:23)
S-ketamine is more potent at the NMDA receptor, making it a more powerful antagonist over R-ketamine. However, both have some potency at the mu-opiate receptor, but S-ketamine is slightly more potent.
Clips
S-ketamine is more potent at NMDA receptors than R-ketamine, which could suggest that at the same dose as R-ketamine, it has more abuse potential.
2:56:30 - 3:03:53 (07:23)
Ketamine
Summary
S-ketamine is more potent at NMDA receptors than R-ketamine, which could suggest that at the same dose as R-ketamine, it has more abuse potential. Ketamine may work for some people on NMDA glutamate receptor antagonists, but others might seek different options due to side effects.