Chapter
Study of Rapamycin and Everolimus Derivatives
1:41:26 - 1:44:51 (03:24)
Study reports that the group given five milligrams of rapamycin once a week had the best response and fewest side effects. A 2014 study found that people in rapamycin, a derivative called everolimus, developed a better immune response, which was contrary to expectations.
Clips
A study conducted by Joan Manick showed that a low-dose of rapamycin drug called Everolimus demonstrated a better immune response and fewer side effects in the group that took five milligrams of the drug once a week, in comparison to the group that took a placebo or higher doses.
1:41:26 - 1:44:15 (02:48)
Summary
A study conducted by Joan Manick showed that a low-dose of rapamycin drug called Everolimus demonstrated a better immune response and fewer side effects in the group that took five milligrams of the drug once a week, in comparison to the group that took a placebo or higher doses.
ChapterStudy of Rapamycin and Everolimus Derivatives
Episode#517: Dr. Peter Attia on Longevity Drugs, Alzheimer's Disease, and the 3 Most Important Levers to Pull
PodcastThe Tim Ferriss Show
The five milligram dose is recommended once a week for producing maximum benefits of metformin without the side effects, whereas 20 milligram dose is accompanied by more side effects than the benefits.
1:44:15 - 1:44:51 (00:35)
Summary
The five milligram dose is recommended once a week for producing maximum benefits of metformin without the side effects, whereas 20 milligram dose is accompanied by more side effects than the benefits. Other interesting candidates for pharmacological interventions that could extend lifespan or health are being discussed.