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Chapter

The debate over allowing individuals to take risks with drugs.
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25:52 - 35:20 (09:28)

In this podcast episode, the host discusses the controversy around individuals being allowed to take risks with drugs and participate in thoughtful trials backed by scientific research, despite not being qualified to understand the risk.

Clips
The discussion centers around the morality and ethics of challenge trials, particularly when developing cancer drugs that require multi-phase trials.
25:52 - 28:24 (02:31)
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Challenge Trials
Summary

The discussion centers around the morality and ethics of challenge trials, particularly when developing cancer drugs that require multi-phase trials. While it's possible to take a specific pathway with the FDA when developing a drug for rare diseases, challenge trials carry a significant amount of risk and require careful consideration.

Chapter
The debate over allowing individuals to take risks with drugs.
Episode
E13: SPACsgiving Special! More promising vaccine news, innovation vs. regulation, reforming higher ed, morality of challenge trials & more
Podcast
All-In with Chamath, Jason, Sacks & Friedberg
The tension between individual responsibility and government regulation exists mainly in fields where people take extreme risks like space exploration or mountain climbing.
28:24 - 30:30 (02:06)
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Government regulation
Summary

The tension between individual responsibility and government regulation exists mainly in fields where people take extreme risks like space exploration or mountain climbing. While the government tries to protect individuals from harm, some people argue that individuals should have the freedom to take risks and responsibility for their own actions.

Chapter
The debate over allowing individuals to take risks with drugs.
Episode
E13: SPACsgiving Special! More promising vaccine news, innovation vs. regulation, reforming higher ed, morality of challenge trials & more
Podcast
All-In with Chamath, Jason, Sacks & Friedberg
People often engage in potentially harmful behaviors like gambling even though they do not have the capacity, generally speaking, to recognize the negative expected value they have.
30:30 - 32:21 (01:51)
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Psychology
Summary

People often engage in potentially harmful behaviors like gambling even though they do not have the capacity, generally speaking, to recognize the negative expected value they have. However, just because behavior is potentially harmful does not mean that people should not be allowed to do it.

Chapter
The debate over allowing individuals to take risks with drugs.
Episode
E13: SPACsgiving Special! More promising vaccine news, innovation vs. regulation, reforming higher ed, morality of challenge trials & more
Podcast
All-In with Chamath, Jason, Sacks & Friedberg
The regulatory capture in the pharmaceutical industry has created an industry that is a retardant of R&D velocity and has driven the structure around risk-taking in drug trials particularly in the US.
32:21 - 35:20 (02:59)
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Drug Industry Regulations
Summary

The regulatory capture in the pharmaceutical industry has created an industry that is a retardant of R&D velocity and has driven the structure around risk-taking in drug trials particularly in the US.

Chapter
The debate over allowing individuals to take risks with drugs.
Episode
E13: SPACsgiving Special! More promising vaccine news, innovation vs. regulation, reforming higher ed, morality of challenge trials & more
Podcast
All-In with Chamath, Jason, Sacks & Friedberg