Chapter
The Effects of Nicotine and Cocaine on Dopamine Reward System
1:08:21 - 1:24:30 (16:08)
Nicotine and cocaine trigger addiction and have negative health effects on all age groups by modulating the dopamine reward system, leading to impairment that can be permanently damaged without intervention. There are parallels between nicotine and cocaine drug pharmacokinetics, which can be a strong reference in understanding addiction mechanisms.
Clips
Nicotine withdrawal can cause agitation and craving for nicotine through a drop in dopamine levels below baseline, leading to addiction from smoking, vaping, dipping, or snuffing.
1:08:21 - 1:14:40 (06:18)
Summary
Nicotine withdrawal can cause agitation and craving for nicotine through a drop in dopamine levels below baseline, leading to addiction from smoking, vaping, dipping, or snuffing. Nicotine delivery by nicotine gum can increase cognitive performance and motor output for quitting discussions.
ChapterThe Effects of Nicotine and Cocaine on Dopamine Reward System
EpisodeNicotine’s Effects on the Brain & Body & How to Quit Smoking or Vaping
PodcastHuberman Lab
This episode briefly explains the impact of cocaine on the human brain's dopamine system and why it is one of the most harmful drugs people can use.
1:14:40 - 1:17:12 (02:31)
Summary
This episode briefly explains the impact of cocaine on the human brain's dopamine system and why it is one of the most harmful drugs people can use. Additionally, it highlights the parallels between the delivery routes for cocaine and nicotine, which can help us better understand drug pharmacokinetics and dopamine.
ChapterThe Effects of Nicotine and Cocaine on Dopamine Reward System
EpisodeNicotine’s Effects on the Brain & Body & How to Quit Smoking or Vaping
PodcastHuberman Lab
The delivery mechanisms for cocaine and nicotine are extremely similar.
1:17:12 - 1:18:38 (01:26)
Summary
The delivery mechanisms for cocaine and nicotine are extremely similar. People snort cocaine or use crack cocaine, which resembles vaping in that it causes rapid increases in psychoactive substances, while vaping causes rapid increases in blood concentrations of nicotine.
ChapterThe Effects of Nicotine and Cocaine on Dopamine Reward System
EpisodeNicotine’s Effects on the Brain & Body & How to Quit Smoking or Vaping
PodcastHuberman Lab
The ingestion of substances that modulate the dopamine system, like nicotine in vaping, can cause negative health effects and may permanently impair the dopamine reward system if not intervened in a deliberate manner; the reward properties of nicotine make it highly addictive and habit-forming.
1:18:38 - 1:24:30 (05:52)
Summary
The ingestion of substances that modulate the dopamine system, like nicotine in vaping, can cause negative health effects and may permanently impair the dopamine reward system if not intervened in a deliberate manner; the reward properties of nicotine make it highly addictive and habit-forming.