Chapter

The Effects of Nicotine on the Brain
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22:14 - 31:03 (08:48)

Nicotine quickly enters the bloodstream and has rapid effects on the brain by binding to the alpha-4-beta-2 receptor, leading to an increase in metabolism and reduction of hunger. The effects are mediated through the main nicotine receptor, alpha-4-beta-2, and take 2 to 15 minutes to appear after ingesting nicotine.

Clips
Nicotinic receptors are a type of acetylcholine receptor found in the brain and body that are activated by the chemical nicotine, leading to changes in cell behavior and increased activity.
22:14 - 23:25 (01:10)
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Nicotinic receptors
Summary

Nicotinic receptors are a type of acetylcholine receptor found in the brain and body that are activated by the chemical nicotine, leading to changes in cell behavior and increased activity.

Chapter
The Effects of Nicotine on the Brain
Episode
Nicotine’s Effects on the Brain & Body & How to Quit Smoking or Vaping
Podcast
Huberman Lab
Nicotine increases metabolism and reduces hunger by binding to the alpha-4-beta-2 receptor in the brain, which is why people may relapse when trying to quit smoking.
23:25 - 25:56 (02:31)
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Nicotine
Summary

Nicotine increases metabolism and reduces hunger by binding to the alpha-4-beta-2 receptor in the brain, which is why people may relapse when trying to quit smoking. The direct effects of nicotine on appetite and metabolism are noticeable 2 to 15 minutes after ingestion.

Chapter
The Effects of Nicotine on the Brain
Episode
Nicotine’s Effects on the Brain & Body & How to Quit Smoking or Vaping
Podcast
Huberman Lab
Nicotine, because it can pass through the blood-brain barrier has rapid effects on the brain, particularly on the mesolimbic reward pathway or the dopamine reward pathway, which can trigger the release of certain neurochemicals from the ventral tegmental area and impinge on nucleus accumbens to increase dopamine levels.
25:56 - 29:31 (03:34)
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Nicotine
Summary

Nicotine, because it can pass through the blood-brain barrier has rapid effects on the brain, particularly on the mesolimbic reward pathway or the dopamine reward pathway, which can trigger the release of certain neurochemicals from the ventral tegmental area and impinge on nucleus accumbens to increase dopamine levels.

Chapter
The Effects of Nicotine on the Brain
Episode
Nicotine’s Effects on the Brain & Body & How to Quit Smoking or Vaping
Podcast
Huberman Lab
The gut microbiota plays a critical role in impacting both our immediate and long-term health.
29:31 - 31:03 (01:32)
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Gut Health, Probiotics, Athletic Greens
Summary

The gut microbiota plays a critical role in impacting both our immediate and long-term health. Athletic Greens provides the necessary probiotics for gut health and can easily be taken on the go, providing individuals with the benefits of gut health while traveling.

Chapter
The Effects of Nicotine on the Brain
Episode
Nicotine’s Effects on the Brain & Body & How to Quit Smoking or Vaping
Podcast
Huberman Lab