Chapter

The Evolution of the Coronavirus
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1:00:02 - 1:07:07 (07:04)

The spread of viruses through mammal evolution led to the creation of binding sites for new classes of proteins, such as the spike protein of the coronavirus. These proteins and other features of the coronavirus are continually evolving as it adapts to different environments and hosts.

Clips
The spike protein is composed of S1 and S2 parts with S1 attaching to the H2 receptor and S2 channeling membrane fusion.
1:00:02 - 1:03:25 (03:22)
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Spike protein
Summary

The spike protein is composed of S1 and S2 parts with S1 attaching to the H2 receptor and S2 channeling membrane fusion. While Orf 8 and Orf 6 are evolving rapidly, the polymerase gene that replicates the genome is evolving slowly.

Chapter
The Evolution of the Coronavirus
Episode
#113 – Manolis Kellis: Human Genome and Evolutionary Dynamics
Podcast
Lex Fridman Podcast
Some viruses in mammalian evolution spread throughout the genome and created new classes of regulatory proteins.
1:03:25 - 1:05:47 (02:22)
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Evolutionary Biology
Summary

Some viruses in mammalian evolution spread throughout the genome and created new classes of regulatory proteins. The evolutionary dynamics and intelligence of viruses in relation to humans is incredible and often overlooked.

Chapter
The Evolution of the Coronavirus
Episode
#113 – Manolis Kellis: Human Genome and Evolutionary Dynamics
Podcast
Lex Fridman Podcast
The binding sites that viruses leave in our genome can actually control our genes and enhance the complexity of mammalian genomes.
1:05:47 - 1:07:07 (01:20)
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Viruses
Summary

The binding sites that viruses leave in our genome can actually control our genes and enhance the complexity of mammalian genomes. It's also important to note that viruses are not intentionally trying to harm humans.

Chapter
The Evolution of the Coronavirus
Episode
#113 – Manolis Kellis: Human Genome and Evolutionary Dynamics
Podcast
Lex Fridman Podcast