Chapter

The Fallibility of the Serotonin Hypothesis
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1:02:31 - 1:13:53 (11:21)

Turning brain regions on can help in treating depression more than just relying on drugs that block the reuptake of serotonin to combat the widely held, but possibly incorrect, theory that the central issue with depression is a lack of serotonin.

Clips
The authors of a controversial paper claim that there is not a serotonin deficit for issues like depression or obsessive-compulsive disorder, but rather that SSRIs, or selective serotonin reuptake inhibitors, work by leaving serotonin in-between two neurons for longer, allowing for more serotonin to be present.
1:02:31 - 1:05:00 (02:28)
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Selective Serotonin Reuptake Inhibitors
Summary

The authors of a controversial paper claim that there is not a serotonin deficit for issues like depression or obsessive-compulsive disorder, but rather that SSRIs, or selective serotonin reuptake inhibitors, work by leaving serotonin in-between two neurons for longer, allowing for more serotonin to be present.

Chapter
The Fallibility of the Serotonin Hypothesis
Episode
Dr. Nolan Williams: Psychedelics & Neurostimulation for Brain Rewiring
Podcast
Huberman Lab
Psychiatry has known for a while that the chemical imbalance theory is wrong.
1:05:00 - 1:06:49 (01:49)
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Psychiatry
Summary

Psychiatry has known for a while that the chemical imbalance theory is wrong. This idea perpetuated through psychiatry 2.0 has caused some misleading information in the lay press.

Chapter
The Fallibility of the Serotonin Hypothesis
Episode
Dr. Nolan Williams: Psychedelics & Neurostimulation for Brain Rewiring
Podcast
Huberman Lab
Psychiatry 3.0 focuses on the circuitry of the brain, providing more effective treatments for psychiatric illnesses such as depression and bringing hope to patients who previously thought they were trapped in their diagnoses.
1:06:49 - 1:10:26 (03:36)
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Psychiatry
Summary

Psychiatry 3.0 focuses on the circuitry of the brain, providing more effective treatments for psychiatric illnesses such as depression and bringing hope to patients who previously thought they were trapped in their diagnoses.

Chapter
The Fallibility of the Serotonin Hypothesis
Episode
Dr. Nolan Williams: Psychedelics & Neurostimulation for Brain Rewiring
Podcast
Huberman Lab
The power of medical treatments lies not just in treating physical ailments, but also in giving individuals a sense of control over their bodies and minds.
1:10:26 - 1:11:01 (00:35)
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Mental Health
Summary

The power of medical treatments lies not just in treating physical ailments, but also in giving individuals a sense of control over their bodies and minds. Through treatments such as stimulation and medication, people can feel empowered to take control of their lives.

Chapter
The Fallibility of the Serotonin Hypothesis
Episode
Dr. Nolan Williams: Psychedelics & Neurostimulation for Brain Rewiring
Podcast
Huberman Lab
The disruptive effects of psilocybin during sessions may allow for new rule considerations and combining of perceptions, leading to improvements in trauma-related symptomology and depression.
1:11:01 - 1:13:53 (02:51)
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Psilocybin
Summary

The disruptive effects of psilocybin during sessions may allow for new rule considerations and combining of perceptions, leading to improvements in trauma-related symptomology and depression.

Chapter
The Fallibility of the Serotonin Hypothesis
Episode
Dr. Nolan Williams: Psychedelics & Neurostimulation for Brain Rewiring
Podcast
Huberman Lab