Chapter

The Future of Aging Research
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1:24:08 - 1:31:35 (07:27)

The development of clinically successful aging research drugs and subsequent human trials requires a much more significant focus on aging and drug trials in animals. The purpose being to gain substantial data that can result in substantial conclusions, instead of limited results from normal human clinical trials.

Clips
The FDA is interested in the ability to scale and deploy a given therapy for a significant number of patients in the population, which can pose challenges when it comes to administering compounds like psychedelic drugs that require a substantial amount of time with a therapist.
1:24:08 - 1:25:57 (01:48)
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FDA
Summary

The FDA is interested in the ability to scale and deploy a given therapy for a significant number of patients in the population, which can pose challenges when it comes to administering compounds like psychedelic drugs that require a substantial amount of time with a therapist. Additionally, there is confusion surrounding how to implement geroscience interventions, which focus on tying together the biology of aging with age-related diseases.

Chapter
The Future of Aging Research
Episode
#610: The Life-Extension Episode — Dr. Matt Kaeberlein on The Dog Aging Project, Rapamycin, Metformin, Spermidine, NAD+ Precursors, Urolithin A, Acarbose, and Much More
Podcast
The Tim Ferriss Show
The geroscience biology of aging space has not seen a path to FDA approval for a drug to target aging, in part because the field has not been effective in communicating its importance to the public and policymakers.
1:25:57 - 1:27:34 (01:37)
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Gerontology
Summary

The geroscience biology of aging space has not seen a path to FDA approval for a drug to target aging, in part because the field has not been effective in communicating its importance to the public and policymakers. A dedicated marketing plan is needed to improve communication and increase funding.

Chapter
The Future of Aging Research
Episode
#610: The Life-Extension Episode — Dr. Matt Kaeberlein on The Dog Aging Project, Rapamycin, Metformin, Spermidine, NAD+ Precursors, Urolithin A, Acarbose, and Much More
Podcast
The Tim Ferriss Show
Clinical trials for lifespan drugs are being developed in companion animals like middle-aged dogs to test their effectiveness on the biology of aging to combat age-related diseases.
1:27:34 - 1:29:20 (01:45)
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lifespan drugs
Summary

Clinical trials for lifespan drugs are being developed in companion animals like middle-aged dogs to test their effectiveness on the biology of aging to combat age-related diseases. The goal is to eventually conduct lifespan clinical trials in people for indications relevant to aging biology.

Chapter
The Future of Aging Research
Episode
#610: The Life-Extension Episode — Dr. Matt Kaeberlein on The Dog Aging Project, Rapamycin, Metformin, Spermidine, NAD+ Precursors, Urolithin A, Acarbose, and Much More
Podcast
The Tim Ferriss Show
A study on the frequency of age-related disease diagnoses found that once a person is diagnosed with one age-related disease, it takes less time before they get the second.
1:29:20 - 1:31:35 (02:15)
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Age-Related Diseases
Summary

A study on the frequency of age-related disease diagnoses found that once a person is diagnosed with one age-related disease, it takes less time before they get the second. The study focused on people of normal health status, who did not have any significant age-related diseases.

Chapter
The Future of Aging Research
Episode
#610: The Life-Extension Episode — Dr. Matt Kaeberlein on The Dog Aging Project, Rapamycin, Metformin, Spermidine, NAD+ Precursors, Urolithin A, Acarbose, and Much More
Podcast
The Tim Ferriss Show