Chapter
The Genetics of Autism and Three-Parent IVF
2:10:31 - 2:15:24 (04:52)
The link between older fathers and their children having a higher probability of autism may be an epigenetic or nature-nurture phenomenon. Three-parent IVF, a procedure that combines the DNA of three individuals, is potentially helpful in cases where older females have unhealthy mitochondrial DNA.
Clips
The children of older fathers tend to have a higher probability of autism, but is it an epigenetic or a nature nurture phenomenon?
2:10:31 - 2:12:42 (02:10)
Summary
The children of older fathers tend to have a higher probability of autism, but is it an epigenetic or a nature nurture phenomenon?
ChapterThe Genetics of Autism and Three-Parent IVF
EpisodeDr. Oded Rechavi: Genes & the Inheritance of Memories Across Generations
PodcastHuberman Lab
Three-parent IVF involves taking the nucleus from the mother's egg and placing it into a younger woman's cytoplasm with healthy mitochondrial DNA, then fertilizing the egg with the father's sperm.
2:12:41 - 2:15:24 (02:42)
Summary
Three-parent IVF involves taking the nucleus from the mother's egg and placing it into a younger woman's cytoplasm with healthy mitochondrial DNA, then fertilizing the egg with the father's sperm. This technique is illegal in the US but legal in the UK and other countries to prevent the production of unhealthy embryos, which could be caused by defective DNA repair machinery in older females producing germ cells with more mutations.