Chapter

The Importance of the Pro-inflammatory Isoform
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2:03:37 - 2:08:38 (05:01)

The pro-inflammatory isoform was crucial 200,000 years ago, offering protection against infections, especially parasitic infections, in the CNS. However, the importance of the isoform in other tissues is uncertain.

Clips
This podcast discusses the E3 isoform and its role in human evolution, specifically when it emerged approximately 50,000 years ago and provided protection against parasitic infections.
2:03:37 - 2:06:24 (02:47)
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Evolution
Summary

This podcast discusses the E3 isoform and its role in human evolution, specifically when it emerged approximately 50,000 years ago and provided protection against parasitic infections.

Chapter
The Importance of the Pro-inflammatory Isoform
Episode
Dr. Peter Attia: Improve Vitality, Emotional & Physical Health & Lifespan
Podcast
Huberman Lab
The origins of Alzheimer's disease are discussed, including the discovery and study of individuals with missing chunks of brain who still function normally, as well as the progression and eventual death of those with Alzheimer's.
2:06:24 - 2:08:38 (02:13)
listen on SpotifyListen on Youtube
Alzheimer's disease
Summary

The origins of Alzheimer's disease are discussed, including the discovery and study of individuals with missing chunks of brain who still function normally, as well as the progression and eventual death of those with Alzheimer's.

Chapter
The Importance of the Pro-inflammatory Isoform
Episode
Dr. Peter Attia: Improve Vitality, Emotional & Physical Health & Lifespan
Podcast
Huberman Lab