Chapter

The Origins of Rapamycin
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1:31:30 - 1:38:21 (06:50)

Scientists Randy Strong and Rich Miller discovered Rapamycin's potential as a longevity drug through NIH-funded research. This drug was originally introduced for organ rejection, but the ITP discovered it had the ability to enhance longevity.

Clips
This episode features a discussion between the host and an expert on the history and breakthroughs of organ transplantation drugs such as Cyclosporin and Rapamycin.
1:31:30 - 1:34:06 (02:36)
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Organ Transplantation
Summary

This episode features a discussion between the host and an expert on the history and breakthroughs of organ transplantation drugs such as Cyclosporin and Rapamycin. They discuss the challenges of suppressing the immune system and the exciting advancements made in drug development over time.

Chapter
The Origins of Rapamycin
Episode
#517: Dr. Peter Attia on Longevity Drugs, Alzheimer's Disease, and the 3 Most Important Levers to Pull
Podcast
The Tim Ferriss Show
Researchers found that a drug initially developed to prevent organ rejection could enhance longevity in mice.
1:34:06 - 1:36:37 (02:30)
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Longevity
Summary

Researchers found that a drug initially developed to prevent organ rejection could enhance longevity in mice. The drug was tested in mice that were at the end of their lives, making the results particularly surprising.

Chapter
The Origins of Rapamycin
Episode
#517: Dr. Peter Attia on Longevity Drugs, Alzheimer's Disease, and the 3 Most Important Levers to Pull
Podcast
The Tim Ferriss Show
Discover the efforts in mitigating heart failure in large dogs, with the study of other markers of health span also showing improvements in canine companions.
1:36:37 - 1:38:21 (01:43)
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Dogs
Summary

Discover the efforts in mitigating heart failure in large dogs, with the study of other markers of health span also showing improvements in canine companions. However, limited funding and high costs make the research challenging.

Chapter
The Origins of Rapamycin
Episode
#517: Dr. Peter Attia on Longevity Drugs, Alzheimer's Disease, and the 3 Most Important Levers to Pull
Podcast
The Tim Ferriss Show