Chapter

The Potential Benefits of Intermittent Dosing of Rapamycin
listen on Spotify
46:51 - 49:51 (03:00)

This podcast discusses the potential benefits of intermittent dosing of rapamycin, including its role in autophagy and the implications of the recent Nobel Prize awarded for the discovery of autophagy. The podcast also covers the recommended dosing schedule and the importance of fasting for maximum effectiveness.

Clips
The process of autophagy is well-known in science, and is the molecular process of self-eating, which was just recognized with a Nobel prize.
46:51 - 47:43 (00:52)
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Autophagy
Summary

The process of autophagy is well-known in science, and is the molecular process of self-eating, which was just recognized with a Nobel prize. Intermittent dosing could be one way to help autophagy clear up damaged goods in your muscle or body.

Chapter
The Potential Benefits of Intermittent Dosing of Rapamycin
Episode
#193: My Life Extension Pilgrimage to Easter Island
Podcast
The Tim Ferriss Show
Christian Devo and David Sinclair discuss the effects of inhibiting mTOR, which activates autophagy and leads to catabolism, is the reason why rapamycin has a positive effect on health span; however, there are no studies on this matter in higher organisms.
47:43 - 48:47 (01:04)
listen on Spotify
mTOR
Summary

Christian Devo and David Sinclair discuss the effects of inhibiting mTOR, which activates autophagy and leads to catabolism, is the reason why rapamycin has a positive effect on health span; however, there are no studies on this matter in higher organisms.

Chapter
The Potential Benefits of Intermittent Dosing of Rapamycin
Episode
#193: My Life Extension Pilgrimage to Easter Island
Podcast
The Tim Ferriss Show
The intermittent dosing of rapamycin could mimic fasting at the molecular level without actually depriving food, thereby triggering normal responses as with fasting.
48:47 - 49:51 (01:04)
listen on Spotify
Rapamycin
Summary

The intermittent dosing of rapamycin could mimic fasting at the molecular level without actually depriving food, thereby triggering normal responses as with fasting. However, constant fasted phases could not be used on animals.

Chapter
The Potential Benefits of Intermittent Dosing of Rapamycin
Episode
#193: My Life Extension Pilgrimage to Easter Island
Podcast
The Tim Ferriss Show