Chapter
The Potential Benefits of Intermittent Dosing of Rapamycin
This podcast discusses the potential benefits of intermittent dosing of rapamycin, including its role in autophagy and the implications of the recent Nobel Prize awarded for the discovery of autophagy. The podcast also covers the recommended dosing schedule and the importance of fasting for maximum effectiveness.
Clips
The process of autophagy is well-known in science, and is the molecular process of self-eating, which was just recognized with a Nobel prize.
46:51 - 47:43 (00:52)
Summary
The process of autophagy is well-known in science, and is the molecular process of self-eating, which was just recognized with a Nobel prize. Intermittent dosing could be one way to help autophagy clear up damaged goods in your muscle or body.
ChapterThe Potential Benefits of Intermittent Dosing of Rapamycin
Episode#193: My Life Extension Pilgrimage to Easter Island
PodcastThe Tim Ferriss Show
Christian Devo and David Sinclair discuss the effects of inhibiting mTOR, which activates autophagy and leads to catabolism, is the reason why rapamycin has a positive effect on health span; however, there are no studies on this matter in higher organisms.
47:43 - 48:47 (01:04)
Summary
Christian Devo and David Sinclair discuss the effects of inhibiting mTOR, which activates autophagy and leads to catabolism, is the reason why rapamycin has a positive effect on health span; however, there are no studies on this matter in higher organisms.
ChapterThe Potential Benefits of Intermittent Dosing of Rapamycin
Episode#193: My Life Extension Pilgrimage to Easter Island
PodcastThe Tim Ferriss Show
The intermittent dosing of rapamycin could mimic fasting at the molecular level without actually depriving food, thereby triggering normal responses as with fasting.
48:47 - 49:51 (01:04)
Summary
The intermittent dosing of rapamycin could mimic fasting at the molecular level without actually depriving food, thereby triggering normal responses as with fasting. However, constant fasted phases could not be used on animals.