Chapter

The Relationship Between Pain and Pleasure.
listen on Spotify
19:50 - 30:18 (10:28)

In neuroscience, pleasure and pain are co-located meaning that the same parts of the brain that process pleasure also process pain. This relationship is significant because indulging in high reward behaviors or substances may lead to a dopamine deficit state, similar to clinical depression.

Clips
The pleasure and pain center of the brain, from the same region, balance the seesaw of addiction.
19:50 - 23:01 (03:11)
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Neuroscience
Summary

The pleasure and pain center of the brain, from the same region, balance the seesaw of addiction. In this episode, Cal Newport and the host talk about research on pleasure, pain, balance and how it affects addiction.

Chapter
The Relationship Between Pain and Pleasure.
Episode
Dr. Anna Lembke: Understanding & Treating Addiction
Podcast
Huberman Lab
The brain's pain mechanism has a higher competitive advantage over the pleasure mechanism in addictive substances or behaviors, causing the feeling of pain to be higher than pleasure.
23:01 - 26:14 (03:12)
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Addiction
Summary

The brain's pain mechanism has a higher competitive advantage over the pleasure mechanism in addictive substances or behaviors, causing the feeling of pain to be higher than pleasure. These behaviors release dopamine in our brains' reward pathway, leading to addiction.

Chapter
The Relationship Between Pain and Pleasure.
Episode
Dr. Anna Lembke: Understanding & Treating Addiction
Podcast
Huberman Lab
Indulging in high-reward behaviors or substances can lead to down-regulating the brain's dopamine receptors and transmission, resulting in a dopamine deficit, similar to clinical depression, and leaving the person in an anhedonic state.
26:14 - 30:18 (04:03)
listen on Spotify
dopamine
Summary

Indulging in high-reward behaviors or substances can lead to down-regulating the brain's dopamine receptors and transmission, resulting in a dopamine deficit, similar to clinical depression, and leaving the person in an anhedonic state.

Chapter
The Relationship Between Pain and Pleasure.
Episode
Dr. Anna Lembke: Understanding & Treating Addiction
Podcast
Huberman Lab