Chapter

The Science Behind Fasting and Longevity
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16:42 - 29:59 (13:17)

Scientist David Sinclair discusses how fasting can lead to longevity and better health, revealing the mechanism that links elevated blood sugar and insulin levels to aging.

Clips
This episode discusses how the rate at which a child enters and goes through puberty may predict overall rates of aging, with early stages of infancy and puberty accelerating aging, but lifespan as a whole being a long developmental arc.
16:42 - 21:58 (05:16)
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Aging
Summary

This episode discusses how the rate at which a child enters and goes through puberty may predict overall rates of aging, with early stages of infancy and puberty accelerating aging, but lifespan as a whole being a long developmental arc. The chemical changes in the epigenome that can be measured also known as the Horvath clock may signal periods of immense vitality are the same periods when we're aging faster.

Chapter
The Science Behind Fasting and Longevity
Episode
Dr. David Sinclair: The Biology of Slowing & Reversing Aging
Podcast
Huberman Lab
Growth hormones can lead to aging, but those with low growth hormone mutations tend to live the longest, proving that caloric restriction and fasting may help with anti-aging.
21:58 - 23:47 (01:48)
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anti-aging
Summary

Growth hormones can lead to aging, but those with low growth hormone mutations tend to live the longest, proving that caloric restriction and fasting may help with anti-aging.

Chapter
The Science Behind Fasting and Longevity
Episode
Dr. David Sinclair: The Biology of Slowing & Reversing Aging
Podcast
Huberman Lab
Drilling into the details of why elevated blood sugar, glucose, and insulin ages us more quickly and how fasting can turn on longevity genes that are important for healthy aging.
23:47 - 29:59 (06:12)
listen on Spotify
Fasting
Summary

Drilling into the details of why elevated blood sugar, glucose, and insulin ages us more quickly and how fasting can turn on longevity genes that are important for healthy aging.

Chapter
The Science Behind Fasting and Longevity
Episode
Dr. David Sinclair: The Biology of Slowing & Reversing Aging
Podcast
Huberman Lab