This transcript talks about the advantages of having a quantified dose of 5-MeO-DMT free base instead of the uncertainty of the dosage in toad venom. It also touches on the fact that studying the milking process or sensitivity to the venom can lead to better understanding of its effects.
Hamilton Morris discusses the science behind alkaloids, the benefits of synthesizing them as opposed to extracting them from plants, and his experiences working with the venom of Bufo alvarius toad.
The more competent someone is in a given task, the more likely they are to underrate their ability, while the less competent they are, the more likely they are to overrate their ability. The conversation then shifts to smart drugs and nootropics, questioning if the true smart drugs have been abandoned because they make people feel abysmally stupid.
Measuring intelligence through the use of nootropics is problematic due to the subjectivity of intelligence and self-assessment. Objective measures of intelligence do not always account for creativity or other cognitive improvements.
The use of nicotine gum is a helpful tool to aid focus and improve memory, but other nootropics like New Pept, PRL853, and Fennel-Paresitam were just okay. There is a question if stimulants are also considered nootropics.
Having a different perspective or approach in problem solving can often lead to finding solutions that may not have been considered before. Psychedelic compounds have gained interest in aiding individuals in gaining different perspectives in problem solving.