Chapter
The Sirtuin story
1:47:41 - 1:54:57 (07:16)
The sirtuins are important regulators of aging, and many studies have been conducted to prove their effectiveness in extending lifespan. Overexpressing the sirtuin gene in worms has been shown to extend their lifespan, leading to hundreds of millions of dollars spent on researching the effectiveness of sirtuins in mammals.
Clips
Researcher David Sinclair explains the discovery and study of sirtuins, a family of proteins that may hold the key to anti-aging, and how the hype surrounding the anti-aging supplement resveratrol may have overshadowed the science behind it.
1:47:41 - 1:53:00 (05:19)
Summary
Researcher David Sinclair explains the discovery and study of sirtuins, a family of proteins that may hold the key to anti-aging, and how the hype surrounding the anti-aging supplement resveratrol may have overshadowed the science behind it.
ChapterThe Sirtuin story
Episode#610: The Life-Extension Episode — Dr. Matt Kaeberlein on The Dog Aging Project, Rapamycin, Metformin, Spermidine, NAD+ Precursors, Urolithin A, Acarbose, and Much More
PodcastThe Tim Ferriss Show
Resveratrol, the molecule found in red wine, has been screened by pharmaceutical companies for various activities, but the media quickly turned it into a justification for drinking wine.
1:53:00 - 1:54:24 (01:23)
Summary
Resveratrol, the molecule found in red wine, has been screened by pharmaceutical companies for various activities, but the media quickly turned it into a justification for drinking wine. In some meetings, it was even talked about for up to 50% of the time in relation to sirtuins.
ChapterThe Sirtuin story
Episode#610: The Life-Extension Episode — Dr. Matt Kaeberlein on The Dog Aging Project, Rapamycin, Metformin, Spermidine, NAD+ Precursors, Urolithin A, Acarbose, and Much More
PodcastThe Tim Ferriss Show
Resveratrol is considered one of the dirtiest drugs because it binds to multiple targets and has many unpredictable effects.
1:54:24 - 1:54:57 (00:33)
Summary
Resveratrol is considered one of the dirtiest drugs because it binds to multiple targets and has many unpredictable effects. This has caused pharmaceutical companies to overlook it despite extensive research.