Chapter
The Use of Ketamine as a Depression Treatment
37:13 - 47:13 (10:00)
The use of ketamine as a depression treatment can be a challenge for some clinicians due to its off-label status and controlled substance classification, but the allowance for S-ketamine to be prescribed on-label may make things easier. There is also some controversy surrounding the importance of the default mode network and downregulation during the ketamine experience.
Clips
Paul Glue and his team at Otago Medical School are conducting extensive research on ketamine analogs and formulations.
37:13 - 38:31 (01:17)
Summary
Paul Glue and his team at Otago Medical School are conducting extensive research on ketamine analogs and formulations. The focus is on slow-release formulations, and the psychoactivity of ketamine metabolites is also being explored.
ChapterThe Use of Ketamine as a Depression Treatment
Episode#619: Dr. Suresh Muthukumaraswamy — LSD Microdosing, Classical Psychedelics vs. Ketamine, Science and Speed in New Zealand, Placebo Options, and The Infinite Possibilities of Studying Mind-Altering Compounds
PodcastThe Tim Ferriss Show
Although ketamine is not an indicated treatment for depression, it has shown to be effective as an off-label treatment.
38:31 - 44:04 (05:33)
Summary
Although ketamine is not an indicated treatment for depression, it has shown to be effective as an off-label treatment. However, clinicians may face challenges prescribing it as it is a controlled substance and not conducive to insurance reimbursement.
ChapterThe Use of Ketamine as a Depression Treatment
Episode#619: Dr. Suresh Muthukumaraswamy — LSD Microdosing, Classical Psychedelics vs. Ketamine, Science and Speed in New Zealand, Placebo Options, and The Infinite Possibilities of Studying Mind-Altering Compounds
PodcastThe Tim Ferriss Show
Clinical response measurement in medical interventions is a complex process, hindered by challenges in diagnosis and the subjective nature of measuring patient experiences.
44:04 - 47:13 (03:09)
Summary
Clinical response measurement in medical interventions is a complex process, hindered by challenges in diagnosis and the subjective nature of measuring patient experiences. The use of complicated interventions further complicates clinical trials, making it difficult to measure and understand their effects.