Chapter

Understanding the Pleasure-Pain Balance and How to Reset It
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02:08 - 15:55 (13:47)

Lemke explains that in our pursuit of pleasure, our brains experience a tilt in the pleasure-pain balance, leading to a decrease in dopamine released every subsequent time we seek pleasure. To reset this balance, we need to enter states where we are not actively seeking pleasure.

Clips
The pleasure-pain balance is controlled by the circuits in our brains that govern our sense of pleasure and pain.
02:08 - 07:14 (05:06)
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Neuroscience
Summary

The pleasure-pain balance is controlled by the circuits in our brains that govern our sense of pleasure and pain. Pursuing pleasure without taking breaks can cause the pain side of this balance to tip, leading to less dopamine release and a decline in our sense of pleasure.

Chapter
Understanding the Pleasure-Pain Balance and How to Reset It
Episode
Understanding & Conquering Depression
Podcast
Huberman Lab
InsideTracker is a personalized nutrition platform that analyzes blood and DNA data to provide recommendations for lifestyle changes, nutrition, and supplementation to improve one's overall health.
07:14 - 10:53 (03:39)
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Personalized Nutrition
Summary

InsideTracker is a personalized nutrition platform that analyzes blood and DNA data to provide recommendations for lifestyle changes, nutrition, and supplementation to improve one's overall health. Vitamin D3 is highlighted as an essential aspect of overall brain and body health.

Chapter
Understanding the Pleasure-Pain Balance and How to Reset It
Episode
Understanding & Conquering Depression
Podcast
Huberman Lab
This episode focuses on major depression, also known as unipolar depression, which is characterized by lows, to distinguish it from bipolar depression.
10:53 - 15:55 (05:02)
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Mental Health
Summary

This episode focuses on major depression, also known as unipolar depression, which is characterized by lows, to distinguish it from bipolar depression. The latter will be discussed in a separate episode.

Chapter
Understanding the Pleasure-Pain Balance and How to Reset It
Episode
Understanding & Conquering Depression
Podcast
Huberman Lab