Chapter
Understanding Whole Genome Duplication in Evolutionary Niche
1:36:16 - 1:46:05 (09:49)
The process of whole genome duplication in evolutionary niche allows for relief of complexity, creating collections of motifs known as regulatory regions with promoters and enhancers, which recruit the machinery required for transcription, export, and translation of RNA molecules.
Clips
The genome works through a digital computer that employs fault tolerance mechanisms.
1:36:16 - 1:39:31 (03:14)
Summary
The genome works through a digital computer that employs fault tolerance mechanisms. DNA motifs form regulatory regions that include promoters and enhancers that are responsible for turning on specific genes, such as those that metabolize coffee.
ChapterUnderstanding Whole Genome Duplication in Evolutionary Niche
Episode#113 – Manolis Kellis: Human Genome and Evolutionary Dynamics
PodcastLex Fridman Podcast
The elegance and complexity of biological systems, from the human genome to viruses like SARS-CoV-2, showcase the key design principle of resilience, which is integral in how biological systems work.
1:39:31 - 1:41:29 (01:57)
Summary
The elegance and complexity of biological systems, from the human genome to viruses like SARS-CoV-2, showcase the key design principle of resilience, which is integral in how biological systems work. This is exemplified through processes like genome duplication and simplification.
ChapterUnderstanding Whole Genome Duplication in Evolutionary Niche
Episode#113 – Manolis Kellis: Human Genome and Evolutionary Dynamics
PodcastLex Fridman Podcast
This episode discusses the role of genome duplication in the evolution of yeast and how fruit-bearing plants created an abundance of sugar in the environment that led to a whole genome duplication.
1:41:29 - 1:43:59 (02:30)
Summary
This episode discusses the role of genome duplication in the evolution of yeast and how fruit-bearing plants created an abundance of sugar in the environment that led to a whole genome duplication. The episode also mentions the use of baker's yeast in bread and wine making and its dominant species in fields of Tuscany.
ChapterUnderstanding Whole Genome Duplication in Evolutionary Niche
Episode#113 – Manolis Kellis: Human Genome and Evolutionary Dynamics
PodcastLex Fridman Podcast
Gene duplication allows for modularity and content-based indexing in biological systems, relieving complexity and allowing for ruthless selection to eliminate any harmful mutations.
1:43:59 - 1:46:05 (02:06)
Summary
Gene duplication allows for modularity and content-based indexing in biological systems, relieving complexity and allowing for ruthless selection to eliminate any harmful mutations.