Chapter

Using optogenetics to study aggression in mice
listen on SpotifyListen on Youtube
17:22 - 27:32 (10:10)

Dayou found a way to evoke aggression in mice by activating specific neurons in the ventromedial hypothalamus using optogenetics. While defensive rage and predatory aggression were mapped out through earlier studies, the encoding of the former remains a mystery.

Clips
Dayoung Oh's work with optogenetics helped to usher in the modern genetic study of circuits in mice, focusing on the ventromedial hypothalamus and how aggression can be evoked in rats and cats through electrical stimulation.
17:22 - 21:15 (03:53)
listen on SpotifyListen on Youtube
Optogenetics
Summary

Dayoung Oh's work with optogenetics helped to usher in the modern genetic study of circuits in mice, focusing on the ventromedial hypothalamus and how aggression can be evoked in rats and cats through electrical stimulation.

Chapter
Using optogenetics to study aggression in mice
Episode
Dr. David Anderson: The Biology of Aggression, Mating, & Arousal
Podcast
Huberman Lab
Researchers have discovered that aggressive behavior can be elicited by stimulating the ventromedial hypothalamus, an area of the brain that contains fear neurons.
21:15 - 24:35 (03:19)
listen on SpotifyListen on Youtube
Ventromedial Hypothalamus
Summary

Researchers have discovered that aggressive behavior can be elicited by stimulating the ventromedial hypothalamus, an area of the brain that contains fear neurons. Using optogenetic stimulation, it was found that male mice displayed offensive aggression that was rewarding when the ventromedial hypothalamus was stimulated.

Chapter
Using optogenetics to study aggression in mice
Episode
Dr. David Anderson: The Biology of Aggression, Mating, & Arousal
Podcast
Huberman Lab
The encoding of defensive aggression in the brain and how it works are still mysteries that haven't been solved.
24:35 - 27:32 (02:57)
listen on SpotifyListen on Youtube
Aggression
Summary

The encoding of defensive aggression in the brain and how it works are still mysteries that haven't been solved. It can be difficult to differentiate between offensive and defensive aggression in mice fights but it's much clearer in rats.

Chapter
Using optogenetics to study aggression in mice
Episode
Dr. David Anderson: The Biology of Aggression, Mating, & Arousal
Podcast
Huberman Lab