Psychedelic companies are facing challenges as they try to take a top down approach to their business, with many of them failing due to their business being not as easy as providing an addictive substance to people.
Nicotine binds to nicotinic receptors in the brain and body, which were named after the compound but already existed in the body due to the presence of naturally occurring chemicals like acetylcholine. Consumption of nicotine through smoking, dipping, snuffing, or vaping leads to the activation of these receptors.
In this episode, the hosts discuss the growing popularity of niche drugs like kratom, but also delve into the topic of hallucinogenics and their potential for mainstream appeal in the future.
While cannabis may have therapeutic benefits, high THC concentration cannabis can increase the probability of psychotic episodes, particularly in young males in their early teens and 20s. It is not as harmless as some proponents suggest and can lead to chronic short-term health issues.
The different types of psychedelic drugs are classified into pharmacological classes. Classic psychedelics, which include LSD and psilocybin, and dissociative psychedelics, like ketamine and dextromethorphan, have different receptor effects that lead to behavioral and subjective effects.