Insulin resistance and sensitivity are as important as genes and genomics when it comes to dementia, and cerebral hypometabolism in menopausal women is driven by the decline in estrogen.
The screening practices for colon cancer are evolving as genetic screening and family history information are considered along with age. Recent literature suggests that colonoscopies may not be necessary for individuals without a family history of colon cancer and who are otherwise generally healthy.
Understanding your LP little a and ApoE can provide insight into the risk of Alzheimer's disease and cardiovascular health.
The study of Alzheimer's has progressed to the cell level, where predictive models can be used to identify how the unique genome of each cell related to cognition and pathology. A collaboration with the Goodyear lab is also examining multi-tissue perturbations in the context of exercise and nutrition to understand how cell-to-cell communications are changing across them.
LDL cholesterol below 30 or an APO-B below 40 mg/dL for a long time means the risk of suffering ASCVD is low. By late 30s or early 40s, APO-B should be lowered to below the 20th percentile, especially for patients with significant genetic abnormalities like familial hypercholesterolemia.