Episode
E35: Biogen's controversial Alzheimer's drug approval, the billionaire space race, real estate, Bitcoin & more
1:35:37
Published: Sun Jun 13 2021
Description
Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Show Notes: 0:00 Bestie intro, Chamath's whereabouts 2:54 Breaking down Biogen's Alzheimer's drug & the FDA's controversial approval 26:46 Billionaire space race: Is Bezos going to space too risky or a smart marketing move? How the space industry is a perfect example of effective government intervention. Can anyone dominate space? 42:55 Big Tech getting back to the office: what is the new normal for companies with thousands of employees? 56:49 Recent factors on the commercial & private real estate markets, inflation head fake 1:05:01 ProPublica's report on billionaire tax returns 1:15:58 Bitcoin toxicity, Snowflake's CEO apologizes for comments on merit & diversity 1:32:48 Science corner with Friedberg: Induced pluripotent stem cells & cloning Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Referenced in the show: https://www.statnews.com/2021/06/07/fda-grants-historicapproval-to-alzheimers-drug-designed-to-slow-cognitive-decline/ https://www.bloomberg.com/news/articles/2021-06-10/harvard-expert-quits-fda-panel-as-furor-over-biogen-drug-grows https://www.instagram.com/p/CP0MSOqnYEo https://www.wsj.com/articles/facebook-lets-more-employees-choose-full-time-remote-work-or-return-to-the-office-11623258049 https://news.yahoo.com/salesforce-ceo-marc-benioff-on-slack-acquisition-135151402.html https://socketsite.com/archives/2021/04/visualizing-all-the-vacant-office-space-in-san-francisco.html https://www.wsj.com/articles/if-you-sell-a-house-these-days-the-buyer-might-be-a-pension-fund-11617544801 https://fred.stlouisfed.org/series/T10YIE https://www.propublica.org/article/the-secret-irs-files-trove-of-never-before-seen-records-reveal-how-the-wealthiest-avoid-income-tax https://www.aqr.com/Insights/Research/Journal-Article/Buffetts-Alpha https://www.ft.com/content/42daca9e-facc-11e7-9bfc-052cbba03425 https://www.bloomberg.com/news/articles/2021-06-07/snowflake-ceo-offers-apologies-support-for-hiring-diversity Tweets: https://twitter.com/Jason/status/1401938511826067457 https://twitter.com/elonmusk/status/1386825367948644352 https://twitter.com/micsolana/status/1403394491143315456 https://twitter.com/Jason/status/140302318070958080
Chapters
The All-In Podcast has Chamath Palihapitiya joining the conversation from an undisclosed location.
00:00 - 01:05 (01:05)
Summary
The All-In Podcast has Chamath Palihapitiya joining the conversation from an undisclosed location. They talk about various topics in this episode.
EpisodeE35: Biogen's controversial Alzheimer's drug approval, the billionaire space race, real estate, Bitcoin & more
PodcastAll-In with Chamath, Jason, Sacks & Friedberg
Biogen stopped a trial for an Alzheimer's drug after negative results, only to surprisingly refile nine months later with data showing those on the highest dose showed a 23% decline in the progression of their Alzheimer's.
01:05 - 06:54 (05:48)
Summary
Biogen stopped a trial for an Alzheimer's drug after negative results, only to surprisingly refile nine months later with data showing those on the highest dose showed a 23% decline in the progression of their Alzheimer's. However, critics argue that the results may not be statistically significant, and therefore do not provide sufficient evidence that the drug works.
EpisodeE35: Biogen's controversial Alzheimer's drug approval, the billionaire space race, real estate, Bitcoin & more
PodcastAll-In with Chamath, Jason, Sacks & Friedberg
The FDA's approval process for drugs can incentivize other startups to enter the market and potentially find a better solution.
06:54 - 13:17 (06:23)
Summary
The FDA's approval process for drugs can incentivize other startups to enter the market and potentially find a better solution. Additionally, a well-structured safety study can allow for faster market entry for drugs that are not harmful to humans.
EpisodeE35: Biogen's controversial Alzheimer's drug approval, the billionaire space race, real estate, Bitcoin & more
PodcastAll-In with Chamath, Jason, Sacks & Friedberg
The high cost of drugs for diseases like Alzheimer's highlights the regulatory mess in the healthcare industry, where pharmaceutical companies charge whatever they want for drugs to make profit, and regulators have to balance accessibility with affordability while ensuring drug efficacy.
13:17 - 20:25 (07:08)
Summary
The high cost of drugs for diseases like Alzheimer's highlights the regulatory mess in the healthcare industry, where pharmaceutical companies charge whatever they want for drugs to make profit, and regulators have to balance accessibility with affordability while ensuring drug efficacy.
EpisodeE35: Biogen's controversial Alzheimer's drug approval, the billionaire space race, real estate, Bitcoin & more
PodcastAll-In with Chamath, Jason, Sacks & Friedberg
As advances in healthcare continue to offer more opportunities for people to potentially cure disease or extend their lives, the cost of approvals for these treatments could have a significant impact on the cost of healthcare overall, resulting in higher inflation.
20:25 - 31:45 (11:19)
Summary
As advances in healthcare continue to offer more opportunities for people to potentially cure disease or extend their lives, the cost of approvals for these treatments could have a significant impact on the cost of healthcare overall, resulting in higher inflation.
EpisodeE35: Biogen's controversial Alzheimer's drug approval, the billionaire space race, real estate, Bitcoin & more
PodcastAll-In with Chamath, Jason, Sacks & Friedberg
The speaker believes that investing in space technology to advance the frontiers of humankind is a worthy program to fund, citing the benefits that could potentially transform humanity.
31:45 - 38:02 (06:16)
Summary
The speaker believes that investing in space technology to advance the frontiers of humankind is a worthy program to fund, citing the benefits that could potentially transform humanity. They compare it to the failures of the government's space shuttle program and advocate for the space industry instead.
EpisodeE35: Biogen's controversial Alzheimer's drug approval, the billionaire space race, real estate, Bitcoin & more
PodcastAll-In with Chamath, Jason, Sacks & Friedberg
The military has important applications for space and there is significant potential for innovation in geothermal energy.
38:02 - 43:33 (05:31)
Summary
The military has important applications for space and there is significant potential for innovation in geothermal energy. However, heavy regulations can stifle innovation cycles, such as those experienced in housing and nuclear energy.
EpisodeE35: Biogen's controversial Alzheimer's drug approval, the billionaire space race, real estate, Bitcoin & more
PodcastAll-In with Chamath, Jason, Sacks & Friedberg
The rise of remote work may lead to a decrease in job-switching and make established employees happier, but the shift to a hybrid model could create new challenges for companies with new hires.
43:33 - 50:54 (07:20)
Summary
The rise of remote work may lead to a decrease in job-switching and make established employees happier, but the shift to a hybrid model could create new challenges for companies with new hires. While commercial real estate may experience decreased utilization of office space, physical plants may still be necessary for certain aspects of work.
EpisodeE35: Biogen's controversial Alzheimer's drug approval, the billionaire space race, real estate, Bitcoin & more
PodcastAll-In with Chamath, Jason, Sacks & Friedberg
Salesforce CEO Marc Benioff discusses the growing trend towards distributed wealth work, in which companies are trying to figure out how to adapt.
50:54 - 57:12 (06:17)
Summary
Salesforce CEO Marc Benioff discusses the growing trend towards distributed wealth work, in which companies are trying to figure out how to adapt. He emphasizes the importance of having a start and end to the workday and mentions that Salesforce is becoming a Slack-centric company.
EpisodeE35: Biogen's controversial Alzheimer's drug approval, the billionaire space race, real estate, Bitcoin & more
PodcastAll-In with Chamath, Jason, Sacks & Friedberg
The discussion centers around the impact of BlackRock, a global investment management corporation, on the housing market and how the corporation's practices are making it more difficult for families to buy homes despite low mortgage rates, creating a potential societal upheaval.
57:12 - 1:05:09 (07:57)
Summary
The discussion centers around the impact of BlackRock, a global investment management corporation, on the housing market and how the corporation's practices are making it more difficult for families to buy homes despite low mortgage rates, creating a potential societal upheaval.
EpisodeE35: Biogen's controversial Alzheimer's drug approval, the billionaire space race, real estate, Bitcoin & more
PodcastAll-In with Chamath, Jason, Sacks & Friedberg
The narrative around taxation is shifting due to stories like Jeff Bezos claiming a $4,000 tax credit on a year when he made billions, despite the principle of taxation being based on recognized gain from income generating events in one's life.
1:05:09 - 1:14:51 (09:42)
Summary
The narrative around taxation is shifting due to stories like Jeff Bezos claiming a $4,000 tax credit on a year when he made billions, despite the principle of taxation being based on recognized gain from income generating events in one's life.
EpisodeE35: Biogen's controversial Alzheimer's drug approval, the billionaire space race, real estate, Bitcoin & more
PodcastAll-In with Chamath, Jason, Sacks & Friedberg
Bitcoin toxicity is making the movement toxic for people, making them not want to participate.
1:14:51 - 1:19:10 (04:18)
Summary
Bitcoin toxicity is making the movement toxic for people, making them not want to participate. It's like cult-like behavior where one cannot criticize Bitcoin without being attacked.
EpisodeE35: Biogen's controversial Alzheimer's drug approval, the billionaire space race, real estate, Bitcoin & more
PodcastAll-In with Chamath, Jason, Sacks & Friedberg
Frank Slootman is a representative and spokesperson for the values of a company that has rapidly grown to a $100 billion valuation.
1:19:10 - 1:30:07 (10:57)
Summary
Frank Slootman is a representative and spokesperson for the values of a company that has rapidly grown to a $100 billion valuation. It's important to have conversations about school choice and understanding the role of nuclear energy in achieving sustainable and clean energy despite potential opposition from political allies.
EpisodeE35: Biogen's controversial Alzheimer's drug approval, the billionaire space race, real estate, Bitcoin & more
PodcastAll-In with Chamath, Jason, Sacks & Friedberg
The podcast discusses the possibility of inducing pluripotent stem cells from any cell in the body and converting them into egg cells to eventually grow a clone of oneself, as well as the potential of using cloning in the biotech industry.
1:30:07 - 1:34:19 (04:11)
Summary
The podcast discusses the possibility of inducing pluripotent stem cells from any cell in the body and converting them into egg cells to eventually grow a clone of oneself, as well as the potential of using cloning in the biotech industry.
EpisodeE35: Biogen's controversial Alzheimer's drug approval, the billionaire space race, real estate, Bitcoin & more
PodcastAll-In with Chamath, Jason, Sacks & Friedberg
Join Jake Al and his co-hosts on a wild ride of laughter and casual conversation in this double episode of the All In Podcast.
1:34:19 - 1:35:29 (01:09)
Summary
Join Jake Al and his co-hosts on a wild ride of laughter and casual conversation in this double episode of the All In Podcast.