Follow the crew: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Invest with the Best... ies!: https://www.thesyndicate.com/allin Referenced in the show: NYT - The Rich Kids Who Want to Tear Down Capitalism https://www.nytimes.com/2020/11/27/style/trust-fund-activism-resouce-generation.html Coinbase - An upcoming story about Coinbase https://blog.coinbase.com/upcoming-story-about-coinbase-2012afc25d27 NYT - ‘Tokenized’: Inside Black Workers’ Struggles at the King of Crypto Start-Ups https://www.nytimes.com/2020/11/27/technology/coinbase-cryptocurrency-black-employees.html Show Notes: 0:00 Besties intro, fashion talk & the All-In Syndicate 3:47 Insights on Slack being acquired by Salesforce for $27.7B - why did they sell, are there any nitpicks, was this a home run for Salesforce? 19:14 Sacks on going up against Marc Benioff and Salesforce Chatter while at Yammer, importance of holding onto winners as long as possible 27:26 Why is DeepMind's AlphaFold a major breakthrough? When will it begin impacting drug discovery? Dangers of AI at scale 47:07 Republican party misfires, Georgia runoff implications, can Trump pre-pardon his family, Biden's effective strategy so far 59:21 Trump's Section 230 gambit, will Trumpism fade away? 1:05:23 Trust Fund socialists 1:26:14 Coinbase vs. NYT round 2, https://www.thesyndicate.com/allin
Experienced investors and tech entrepreneurs, David Sacks, David Friedberg, and Chamath Palihapitiya reunite to discuss strategies for investing, entrepreneurship, and challenges of wealth accumulation.
Slack's failure to develop an effective sales team is what ultimately led to its acquisition by Salesforce for $27.7 billion, according to Ben Thompson. He argues that Slack's DNA and the culture of product-based SaaS companies often lead to a reflexive dislike for sales.
Salesforce's acquisition of Slack could have been from a combination of fear of Microsoft and a desire to add enterprise-scale abilities to the platform. Though the acquisition leaves the future of the platform's execution unknown, Salesforce may have created a bid as a solution to solve Slack's ability to cross-sell and up-sell products at an enterprise level.
Ross Mayfield shares his experience of selling stocks and starting a successful social collaboration enterprise, Socialtext, and how it led to the company being sold to Microsoft.
Alpha Fold is now able to predict the shape of a protein from a sequence of amino acids using a database of structural protein shapes, which allows for designing proteins with specific functions.
Discussing the power of the Alpha series gaming engines, which have beaten humans and computers in chess and many other games.
With the advent of digital biology being accessible to everyone, the biodefense industry will become one of the largest industries on the planet, with the ability to design a specific protein that can cause harm or create a new virus that can be neutralized immediately with printed vaccines.
The AlphaFold technique will lead to the funding of many startups with novel protein ideas that will be used in drug discovery, resulting in an increase in the importance of Biodefense.
The upcoming Georgia senate runoffs will determine which party controls the Senate and will have a significant impact on the future policies proposed by the government.
The speaker discusses Joe Biden's good campaign strategy and how he is a gaff machine when speaking spontaneously. They also mention the potential issue with the Southern District of New York.
The guest speaker highlights Trump's strategic moves to target the independents needed to win over the upcoming election, by appealing to the base and preventing Republicans from marking him as a radical.
As people grow older and accumulate wealth that they would have to pass down to their children and grandchildren, they usually become more conservative, fearing what could be lost through liberal ideas. Political figures have also experienced a backlash from their constituents for supporting radical ideas that could impede their re-elections.
The next 20 years will witness the most enormous wealth transfer, where $30 trillion will change hands. While it's essential to talk about this transfer and how to eradicate student debt, some organizations will scam inheritance recipients out of their trust funds.
Coinbase's preemptive announcement of an upcoming New York Times article created a spike protein that trained the immune system of Silicon Valley to be ready for the potentially negative article, causing controversy among reporters.
The hosts of the All-In podcast talk about potential investing opportunities for their listeners and plan to involve them in their future endeavors.