0:00 Chamath's preferred cosplay 1:35 Reflecting on bad investment decisions and markup dynamics 15:20 Rising tensions between US and Russia over Ukraine, Putin's demands, NATO negotiations as the underreported key piece, Obama's savvy Russia dealings 39:16 Bill Ackman buys the Netflix dip, Tesla and Microsoft crush earnings, the Fed signals rate hikes 55:18 Altos Labs raises $3B in the largest Seed round ever, incredible Yamanaka factors breakthrough, dynamics of a richly capitalized bio-moonshot 1:04:08 The Stripe Mafia, Bolt CEO punches up, reflecting on old emails Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Intro Video Credit: https://twitter.com/TheZachEffect Referenced in the show: https://www.bloomberg.com/opinion/articles/2013-05-30/bitcoin-the-perfect-schmuck-insurance https://twitter.com/DavidSacks/status/1480716684038049796 https://medium.com/@jason/do-the-work-skip-the-party-8f2864560195#724a--share-10-78 https://www.nytimes.com/2022/01/16/world/europe/russia-ukraine-invasion.html https://www.defense.gov/News/Transcripts/Transcript/Article/2910061/pentagon-press-secretary-john-kirby-holds-a-press-briefing https://www.theatlantic.com/magazine/archive/2016/04/the-obama-doctrine/471525 https://www.history.com/news/nato-article-5-meaning-history-world-war-2 https://www.latimes.com/opinion/op-ed/la-oe-shifrinson-russia-us-nato-deal--20160530-snap-story.html https://www.worldometers.info/gdp/gdp-by-country https://www.atlanticcouncil.org/blogs/natosource/obama-does-not-believe-invading-ukraine-or-saving-assad-makes-putin-a-player https://www.euractiv.com/section/global-europe/news/germany-agrees-to-axe-nord-stream-2-if-russia-invades-ukraine https://www.wsj.com/articles/william-ackman-takes-stake-in-netflix-11643236690 https://tesla-cdn.thron.com/static/WIIG2L_TSLA_Q4_2021_Update_O7MYNE.pdf?xseo=&response-content-disposition=inline%3Bfilename%3D%22tsla-q4-and-fy-2021-update.pdf%22 https://www.microsoft.com/en-us/Investor/earnings/FY-2022-Q2/press-release-webcast https://www.cnbc.com/2022/01/26/fed-decision-january-2022-.html https://www.tcv.com/tcv-insights/netflix-case-study https://www.cnbc.com/2021/11/16/peloton-files-to-sell-1-billion-in-stock-offering-shares-drop.html https://www.drugdiscoverytrends.com/biotech-altos-labs-emerges-with-3b-in-funding-to-focus-on-cellular-rejuvenation-programming https://www.biorxiv.org/content/10.1101/2022.01.20.477063v1.full.pdf https://twitter.com/theryanking/status/1485784823641755648 https://twitter.com/shaunmmaguire/status/1486082835974811650 https://twitter.com/Jason/status/1486113945790214146 https://twitter.com/shaunmmaguire/status/1486114773209006080 https://twitter.com/Jason/status/1486121975311339520 https://my.pitchbook.com/profile/107633-08/company/profile#deal-history/102358-00T
The podcast discusses the power dynamics of old Italian culture and the role of women in decision-making, as well as the hobby of cosplay.
The podcast features Chamath Palihapitiya, David Friedberg, and David Sacks discussing stock trading strategies and how to insulate oneself from market turmoil. The episode also reflects on past mistakes in trading.
The prices of private market shares are coming down due to the slowdown of crossover investors like Tiger and KOTU who have deployed a lot of money, according to sources, causing interests in funds like Calm and Robinhood to decrease.
The conflict between the US and Russia has a long historical context, with actions by both sides contributing to the current tensions. The possibility of military engagement is without historical precedent during the Cold War.
The lack of economic productivity gains and trade issues has led countries to seek growth through foreign interventions, which may not be the best investment, while sustainable energy would be a better option, but the media's coverage and rhetoric in humanitarian sentiments would eventually lead to stupid foreign interventions that manufacture conflict and growth for the US.
The relationship between the US and Russia is complicated by a number of factors, including the fact that those who make foreign policy have not served in the military and don't have children in harm's way. Is there a potential for deepening this relationship and utilizing it against the growing power of China?
Microsoft reported a revenue of $51.7 billion and net income of $18.8 billion, up by 20% YoY. The Fed's plan of rate hikes this year and selling assets worth $9 trillion may have a significant impact, while China and Germany have also made economic moves.
The ongoing supply chain problems could lead to businesses unexpectedly suffering 20-30% reductions in revenue due to product shortages. Despite the current uncertainties, there are opportunities for growth and long-term success for some businesses in the market.
The latest biotech innovation is focused on reversing the age of individuals using drugs. Scientists have been experimenting with mice and have garnered some incredible results that will revolutionize the way we look at the aging process.
The speaker argues that startups should hire a diverse group of people and take multiple shots on goal simultaneously to increase their chances of success. This approach allows for the possibility of a single successful startup being worth billions of dollars.
A discussion about Stripe, the biggest company to come out of YC ever and their success strategy of blocking top VCs as well as their ability to raise a lot of money at high valuations. The conversation also touches on the struggle of VCs when investing in companies at high valuations.
The speaker shares insights into being a price taker as an investor, mentioning that sometimes the market sets the price regardless of the investor's preferences.