Episode

How mRNA Vaccines Work
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1:00:44
Published: Tue Nov 02 2021
Description

The two mRNA Covid vaccines are the first vaccines to come out of a new field of immunology and represent such an amazing leap forward that they are taking us into a new era of medicine. Learn all about them so you can set your uncle straight. Learn more about your ad-choices at https://www.iheartpodcastnetwork.comSee omnystudio.com/listener for privacy information.

Chapters
Join David Eagleman on Inner Cosmos as he explores the relationship between our brains and experiences, tackling questions such as the possibility of creating new senses.
00:00 - 01:26 (01:26)
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neuroscience
Summary

Join David Eagleman on Inner Cosmos as he explores the relationship between our brains and experiences, tackling questions such as the possibility of creating new senses.

Episode
How mRNA Vaccines Work
Podcast
Stuff You Should Know
The mRNA vaccines represent a new path forward and it is hard to overstate just how big of a breakthrough it was for them, as they differ from traditional vaccines.
01:27 - 06:49 (05:21)
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mRNA vaccines
Summary

The mRNA vaccines represent a new path forward and it is hard to overstate just how big of a breakthrough it was for them, as they differ from traditional vaccines.

Episode
How mRNA Vaccines Work
Podcast
Stuff You Should Know
The use of different nucleotides during mRNA vaccine research has allowed for the creation of a vaccine that appears natural enough to fool nature.
06:49 - 16:20 (09:31)
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mRNA vaccines
Summary

The use of different nucleotides during mRNA vaccine research has allowed for the creation of a vaccine that appears natural enough to fool nature. With the ability to read and write genetic codes, it's possible to create a template for a specific virus, such as the SARS-CoV-2 coronavirus.

Episode
How mRNA Vaccines Work
Podcast
Stuff You Should Know
The mRNA in vaccines is now produced outside of the body and then injected, allowing it to travel to the cytoplasm of the cell to produce a protein.
16:20 - 19:29 (03:09)
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mRNA Vaccines
Summary

The mRNA in vaccines is now produced outside of the body and then injected, allowing it to travel to the cytoplasm of the cell to produce a protein.

Episode
How mRNA Vaccines Work
Podcast
Stuff You Should Know
This podcast discusses how mRNA vaccines work through the metaphor of a training session, even when the strands can be too big to permeate the cell.
19:29 - 23:34 (04:04)
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mRNA vaccines
Summary

This podcast discusses how mRNA vaccines work through the metaphor of a training session, even when the strands can be too big to permeate the cell.

Episode
How mRNA Vaccines Work
Podcast
Stuff You Should Know
To achieve a good immunization, both the innate and adaptive immune system of the body should be triggered without over-activating them.
23:34 - 27:16 (03:41)
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Immune System
Summary

To achieve a good immunization, both the innate and adaptive immune system of the body should be triggered without over-activating them. Engaging these two immune systems will result in a better immune response.

Episode
How mRNA Vaccines Work
Podcast
Stuff You Should Know
Our body creates immunity to viruses like COVID-19 through a process where muscle cells produce viral proteins which are taken up by lymph nodes and shown to T and B cells, triggering an innate and an adaptive immune response.
27:17 - 35:07 (07:49)
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Immunity
Summary

Our body creates immunity to viruses like COVID-19 through a process where muscle cells produce viral proteins which are taken up by lymph nodes and shown to T and B cells, triggering an innate and an adaptive immune response. This response creates antibodies to fight the virus and memorizes them for future attacks.

Episode
How mRNA Vaccines Work
Podcast
Stuff You Should Know
This podcast aims to tackle unusual questions that help us better understand our lives, including the relationship between our brains and experiences, as well as the science behind COVID vaccines.
35:07 - 40:05 (04:58)
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Neuroscience, COVID-19, Vaccines
Summary

This podcast aims to tackle unusual questions that help us better understand our lives, including the relationship between our brains and experiences, as well as the science behind COVID vaccines. Listeners can expect to get straightforward explanations about complex topics, and even ideas about how to discuss them with their "weird uncle" at Thanksgiving.

Episode
How mRNA Vaccines Work
Podcast
Stuff You Should Know
Scientists have developed a way to manufacture RNA vaccines outside the human body by using bacteriophages and plasmid DNA, rather than relying on cellular cultures.
40:05 - 45:09 (05:03)
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Science
Summary

Scientists have developed a way to manufacture RNA vaccines outside the human body by using bacteriophages and plasmid DNA, rather than relying on cellular cultures. They discovered this technique in the 1980s at Brookhaven National Lab and it has provided a new breakthrough for efficient RNA transcription and vaccine creation even beyond COVID-19.

Episode
How mRNA Vaccines Work
Podcast
Stuff You Should Know
The development of the COVID-19 vaccine was an applaudable feat, with researchers able to utilize a large sample size due to the massive outbreak of the virus around the world.
45:09 - 53:01 (07:52)
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COVID-19 vaccine
Summary

The development of the COVID-19 vaccine was an applaudable feat, with researchers able to utilize a large sample size due to the massive outbreak of the virus around the world. Despite the speed of the vaccine's development, it was done in a safe manner, with no compromise on the quality of the research conducted.

Episode
How mRNA Vaccines Work
Podcast
Stuff You Should Know
The idea that mRNA vaccines can alter your DNA is a common misconception among vaccine-hesitant people.
53:01 - 57:19 (04:17)
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mRNA vaccines
Summary

The idea that mRNA vaccines can alter your DNA is a common misconception among vaccine-hesitant people. However, mRNA vaccines work outside of the cell, in the cytoplasm, and do not integrate with the cell's DNA.

Episode
How mRNA Vaccines Work
Podcast
Stuff You Should Know
Wells Adams and Tyler Florence introduce their new immersive fiction podcast on iHeart Radio.
57:19 - 59:30 (02:10)
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Podcast
Summary

Wells Adams and Tyler Florence introduce their new immersive fiction podcast on iHeart Radio. Visit the iHeart Radio app or Apple Podcasts for more podcasts.

Episode
How mRNA Vaccines Work
Podcast
Stuff You Should Know