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Episode

Selects: How LSD Works
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1:26:00
Published: Sat Sep 24 2022
Description

In 1943 Swiss chemist Albert Hofman discovered he'd created what may be the most potent hallucinogen known to humankind. Then he took a bike ride. Learn about the chemistry, neurology, history and cultural impact of LSD-25 in this classic episode.See omnystudio.com/listener for privacy information.

Chapters
Lance Bass hosts a podcast that tells the story about Albert Hoffman's LSD experiment on himself and a Russian astronaut who found himself stranded in space with no country to bring him down.
00:00 - 04:30 (04:30)
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Podcast
Summary

Lance Bass hosts a podcast that tells the story about Albert Hoffman's LSD experiment on himself and a Russian astronaut who found himself stranded in space with no country to bring him down.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
The creation of LSD 73 years ago on bicycle day had a profound effect on the world, with few man-made substances having a more significant impact.
04:30 - 06:43 (02:12)
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LSD
Summary

The creation of LSD 73 years ago on bicycle day had a profound effect on the world, with few man-made substances having a more significant impact. Its influence can be seen in popular culture in the West.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
The conversation centers around the dangers of drug use and how some people use tragic situations to push back against the changing social norms.
06:43 - 09:28 (02:44)
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Drug use
Summary

The conversation centers around the dangers of drug use and how some people use tragic situations to push back against the changing social norms. Art Linkletter's experience with his daughter's suicide is discussed in relation to his moral crusade against drugs.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
The LSD hysteria affected the understanding of consciousness, treatment of mental illness and spread misconceptions about its effect on chromosomes, offspring and the involvement of the CIA in unethical experiments.
09:28 - 14:44 (05:16)
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LSD
Summary

The LSD hysteria affected the understanding of consciousness, treatment of mental illness and spread misconceptions about its effect on chromosomes, offspring and the involvement of the CIA in unethical experiments.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
The history of LSD starts with Albert Hofmann's tinkering with lysergic acid, which eventually led to the creation of LSD-25 in 1938.
14:44 - 18:33 (03:48)
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LSD
Summary

The history of LSD starts with Albert Hofmann's tinkering with lysergic acid, which eventually led to the creation of LSD-25 in 1938. However, it wasn't until five years later that Hofmann rediscovered the drug and its hallucinogenic properties.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
Albert Hoffman accidentally ingested LSD and experienced its effects, leading him to later intentionally take the drug.
18:33 - 20:31 (01:58)
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LSD
Summary

Albert Hoffman accidentally ingested LSD and experienced its effects, leading him to later intentionally take the drug.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
A man takes 250 micrograms of acid, which leads to a bad trip for an hour and a half until a doctor intervenes.
20:31 - 25:43 (05:11)
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drugs
Summary

A man takes 250 micrograms of acid, which leads to a bad trip for an hour and a half until a doctor intervenes.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
The drug became popular in the psychiatric setting due to its beneficial effects, but as it caught on, it was marketed heavily, resulting in large numbers of doses sold.
25:43 - 29:14 (03:30)
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Psychotronic drugs
Summary

The drug became popular in the psychiatric setting due to its beneficial effects, but as it caught on, it was marketed heavily, resulting in large numbers of doses sold. Its effect was not limited to the US; it had an impact in Europe as well.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
From its arrival in the 1950s to its eventual classification as a Schedule I drug, LSD underwent a dramatic rise and fall in popularity and perception, shifting from a party drug to a potential therapeutic tool before being banned outright.
29:14 - 32:23 (03:09)
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LSD
Summary

From its arrival in the 1950s to its eventual classification as a Schedule I drug, LSD underwent a dramatic rise and fall in popularity and perception, shifting from a party drug to a potential therapeutic tool before being banned outright.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
The hosts discuss the perceived coolness of a fictional character known for his tech-savvy skills and distinctive fashion sense, including black boots and flannel shirts.
32:23 - 35:51 (03:27)
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Fictional Characters
Summary

The hosts discuss the perceived coolness of a fictional character known for his tech-savvy skills and distinctive fashion sense, including black boots and flannel shirts.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
This episode discusses the history of how LSD was discovered and the chemistry behind its creation.
35:51 - 40:52 (05:00)
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LSD
Summary

This episode discusses the history of how LSD was discovered and the chemistry behind its creation. It also delves into the effects of LSD and its potential uses in medicine.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
The weight of LSD and how it is measured by the criminal justice system is explored, as well as the art surrounding the drug.
40:52 - 44:55 (04:02)
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LSD
Summary

The weight of LSD and how it is measured by the criminal justice system is explored, as well as the art surrounding the drug.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
Tripping on LSD may lead to hallucinations that provide a profound impact on the brain.
44:56 - 49:08 (04:11)
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LSD
Summary

Tripping on LSD may lead to hallucinations that provide a profound impact on the brain. It's important to trip with experienced people in a calm place for a safe experience.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
LSD induces an emotional hangover by mimicking the shape of serotonin and hijacking the serotonin receptors, which can lead to both positive and negative experiences during the trip.
49:08 - 54:18 (05:10)
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LSD
Summary

LSD induces an emotional hangover by mimicking the shape of serotonin and hijacking the serotonin receptors, which can lead to both positive and negative experiences during the trip. This can cause a whoa kind of feeling that lasts up to 12 hours after the trip.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
A new podcast hosted by a comedy superstar and television icon from the 90s has been announced, with the podcast featuring a tech-savvy character as well.
54:18 - 58:03 (03:44)
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Podcasts
Summary

A new podcast hosted by a comedy superstar and television icon from the 90s has been announced, with the podcast featuring a tech-savvy character as well.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
Brain scans of people under the influence of LSD for the first time in human history have opened up some new ideas for what's going on during an acid trip, supporting the theory that drugs like LSD and psilocybin tone down the thalamus's activity, resulting in changes in perception and understanding of concepts like the universe and reality.
58:03 - 1:04:08 (06:05)
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LSD
Summary

Brain scans of people under the influence of LSD for the first time in human history have opened up some new ideas for what's going on during an acid trip, supporting the theory that drugs like LSD and psilocybin tone down the thalamus's activity, resulting in changes in perception and understanding of concepts like the universe and reality.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
Studies have shown that LSD therapy can have a positive impact on individuals suffering from various mental health conditions, including anxiety and depression.
1:04:08 - 1:07:05 (02:56)
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LSD therapy
Summary

Studies have shown that LSD therapy can have a positive impact on individuals suffering from various mental health conditions, including anxiety and depression. While more research is needed, early results suggest potential benefits for those seeking alternative treatment options.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
Despite popular belief, acid flashbacks are not caused by leftover LSD in the body, but rather by the brain's ability to recall vivid experiences.
1:07:06 - 1:15:56 (08:50)
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LSD
Summary

Despite popular belief, acid flashbacks are not caused by leftover LSD in the body, but rather by the brain's ability to recall vivid experiences.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
In this podcast, the host discusses the meaning behind the counterculture phrase "Turn On".
1:15:56 - 1:20:37 (04:40)
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counterculture
Summary

In this podcast, the host discusses the meaning behind the counterculture phrase "Turn On". Despite it being interpreted as promoting drug use and laziness, the phrase actually encourages individuals to tap into their full potential and creativity.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
This episode discusses the toxic effects of newer forms of LSD, such as 25i-NBOMe and one P LSD.
1:20:37 - 1:24:17 (03:40)
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LSD
Summary

This episode discusses the toxic effects of newer forms of LSD, such as 25i-NBOMe and one P LSD. These drugs have shown to cause overdoses and even death.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know
Unpacking the Toolbox is a podcast with undisclosed contents, and The Last Soviet is a podcast about Lance Bass's and a Russian astronaut's space training.
1:24:17 - 1:26:10 (01:52)
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Podcasts
Summary

Unpacking the Toolbox is a podcast with undisclosed contents, and The Last Soviet is a podcast about Lance Bass's and a Russian astronaut's space training.

Episode
Selects: How LSD Works
Podcast
Stuff You Should Know