Chapter
Can Fasting or Nutritional Ketosis Help Mitigate Neurodegenerative Diseases?
24:02 - 30:58 (06:55)
The host asks the guest about the implications of fasting, nutritional ketosis, or exogenous ketones for preventing Alzheimer's or Parkinson's disease, given that beta hydroxybutyrate can affect gene expression. The guest explains that there have been some promising results in animal studies, but more research needs to be done.
Clips
The macronutrient ratio of a ketogenic diet mimics the metabolic physiology of fasting, which is the fastest way to enter ketosis.
24:02 - 25:46 (01:43)
Summary
The macronutrient ratio of a ketogenic diet mimics the metabolic physiology of fasting, which is the fastest way to enter ketosis. Ketones produced during fasting can also have positive effects on gene expression.
ChapterCan Fasting or Nutritional Ketosis Help Mitigate Neurodegenerative Diseases?
Episode#117: Dom D'Agostino on Fasting, Ketosis, and The End of Cancer
PodcastThe Tim Ferriss Show
Beta Hydroxybutyrate acts as a class one and class two inhibitor and can activate genes that play a role in enhancing endogenous antioxidant mechanisms, suppressing an inflammatory pathway that is linked to age-related chronic diseases.
25:47 - 27:49 (02:01)
Summary
Beta Hydroxybutyrate acts as a class one and class two inhibitor and can activate genes that play a role in enhancing endogenous antioxidant mechanisms, suppressing an inflammatory pathway that is linked to age-related chronic diseases.
ChapterCan Fasting or Nutritional Ketosis Help Mitigate Neurodegenerative Diseases?
Episode#117: Dom D'Agostino on Fasting, Ketosis, and The End of Cancer
PodcastThe Tim Ferriss Show
The applications of fasting, nutritional ketosis, and exogenous ketones in the prevention and mitigation of neurodegenerative diseases such as Alzheimer's and Parkinson's, as well as the combination of fasting with chemotherapy in cancer treatment.
27:49 - 30:58 (03:09)
Summary
The applications of fasting, nutritional ketosis, and exogenous ketones in the prevention and mitigation of neurodegenerative diseases such as Alzheimer's and Parkinson's, as well as the combination of fasting with chemotherapy in cancer treatment.