Chapter
Circadian rhythms could improve cancer treatment
36:33 - 51:23 (14:49)
Cancer drugs infused at certain times of day can reduce toxicity and boost effectiveness against cancer cells. Exploiting circadian rhythms may improve the efficacy and reduce the side effects of treatments for diseases, especially cancer.
Clips
Researchers are exploring the relationship between our clock genes and disease treatments, such as chemotherapy, to determine if aligning treatments with patients' circadian rhythms can reduce side effects and improve efficacy.
36:33 - 41:34 (05:01)
Summary
Researchers are exploring the relationship between our clock genes and disease treatments, such as chemotherapy, to determine if aligning treatments with patients' circadian rhythms can reduce side effects and improve efficacy. By understanding how clock genes impact metabolism and inflammation, scientists hope to develop targeted drug therapies to prevent disease and promote healthy aging.
ChapterCircadian rhythms could improve cancer treatment
EpisodeThe Sunday Read: ‘The Quest by Circadian Medicine to Make the Most of Our Body Clocks’
PodcastThe Daily
Researchers face difficulty in conducting experiments to determine the impact of drug timing on survival due to the need for diverse patients and assigning them random time slots.
41:34 - 47:18 (05:44)
Summary
Researchers face difficulty in conducting experiments to determine the impact of drug timing on survival due to the need for diverse patients and assigning them random time slots. Results from a study published in Lancet Oncology suggest that patients with metastatic melanoma who receive immunotherapy infusions after 4.30 pm do not live as long as those who receive them earlier.
ChapterCircadian rhythms could improve cancer treatment
EpisodeThe Sunday Read: ‘The Quest by Circadian Medicine to Make the Most of Our Body Clocks’
PodcastThe Daily
A team of researchers are analyzing electronic medical records to understand how the timing of medication can impact their effectiveness.
47:18 - 51:23 (04:04)
Summary
A team of researchers are analyzing electronic medical records to understand how the timing of medication can impact their effectiveness. Their goal is to improve the standard practices in logging the times of procedures to gain a better understanding of how time affects 48 pharmacological or surgical treatments.