Factors such as protein diet, lipid ratios, and certain genetic factors can affect weight loss and hormonal control in individuals, and measuring biomarkers such as LDL cholesterol, HbA1C, and triglycerides can help identify areas of improvement in diet and lifestyle.
Exercise and changing one's diet can both improve depressive scores according to studies, and combined they are even more effective, as hormones regulating and self-regulating can help with treatment.
There is a link between diet, lifestyle, obesity, inflammation, immune cells and depression. Just having fat cells produce inflammatory cytokines that create low-grade inflammation, which requires a lot of energy from the immune cells, leading to fatigue and the potential to develop depression.
This podcast episode explores whether genetics or DNA factors can hold someone back from losing weight after many attempts, and suggests that measuring biomarkers in blood may be necessary to understand and overcome such barriers.
The ratio of saturated fat to polyunsaturated and monounsaturated fats, as well as genetics, metabolism, and hormones, can influence a person's ability to lose or gain weight, and it may take a strong stressor such as a long fast to reset those hormones.