Chapter
Familial Hypercholesterolemia and ApoB Particles
1:14:11 - 1:24:39 (10:28)
The ApoB family consists of VLDL, IDL, LDL, and LPa, which is the worst of them all, and lowering ApoB can lead to a decrease in cholesterol levels. This is important for people with familial hypercholesterolemia, who have very high levels of cholesterol and LDL cholesterol.
Clips
This podcast discusses the different types of lipoproteins in the ApoB family and their roles in transporting fat in our body.
1:14:11 - 1:16:42 (02:30)
Summary
This podcast discusses the different types of lipoproteins in the ApoB family and their roles in transporting fat in our body. It also highlights the LPa, which is considered the worst actor of the bunch.
ChapterFamilial Hypercholesterolemia and ApoB Particles
Episode#517: Dr. Peter Attia on Longevity Drugs, Alzheimer's Disease, and the 3 Most Important Levers to Pull
PodcastThe Tim Ferriss Show
The concern of lowering ApoB is also lowering cholesterol.
1:16:42 - 1:21:05 (04:22)
Summary
The concern of lowering ApoB is also lowering cholesterol. Total Cholesterol is a 50% reduction in serum cholesterol, which results in a 5% to 10% reduction in total body cholesterol.
ChapterFamilial Hypercholesterolemia and ApoB Particles
Episode#517: Dr. Peter Attia on Longevity Drugs, Alzheimer's Disease, and the 3 Most Important Levers to Pull
PodcastThe Tim Ferriss Show
A New Cholesterol Drug Mimics a Genetic Mutation That Appears to be Protective Against Many Diseases
Researchers in Toronto have developed a drug designed to mimic a genetic mutation that reduces the risk of conditions like cardiovascular disease in people with familial hypercholesterolemia.
1:21:05 - 1:23:19 (02:14)
Summary
Researchers in Toronto have developed a drug designed to mimic a genetic mutation that reduces the risk of conditions like cardiovascular disease in people with familial hypercholesterolemia. The mutation affects PCSK9, and leads to a hyper-functioning protein which constantly degrades LDL receptors.
ChapterFamilial Hypercholesterolemia and ApoB Particles
Episode#517: Dr. Peter Attia on Longevity Drugs, Alzheimer's Disease, and the 3 Most Important Levers to Pull
PodcastThe Tim Ferriss Show
A discussion on statins and PCSK9 inhibitors and how important they are in preventing heart diseases while being relatively safe drugs.
1:23:19 - 1:24:39 (01:20)
Summary
A discussion on statins and PCSK9 inhibitors and how important they are in preventing heart diseases while being relatively safe drugs.