Chapter
Piecing Together the Regulatory Circuitry of the Brain with Single Cell RNA Sequencing
2:08:40 - 2:15:56 (07:16)
This podcast episode discusses the use of three different technologies to analyze the regulatory circuitry of the brain in 1,500 individuals across multiple brain regions, both at the DNA and RNA level, and how it can be used to explore different disorders including schizophrenia, Alzheimer's, and autism.
Clips
By using single cell RNA sequencing, researchers can study the regulatory circuitry of every single type of neuron, astrocyte, oligotendrocyte, and microglial cell inside the brains of 1,500 individuals across various brain regions and disorders, including schizophrenia, Alzheimer's, and autism.
2:08:40 - 2:15:11 (06:31)
Summary
By using single cell RNA sequencing, researchers can study the regulatory circuitry of every single type of neuron, astrocyte, oligotendrocyte, and microglial cell inside the brains of 1,500 individuals across various brain regions and disorders, including schizophrenia, Alzheimer's, and autism.
ChapterPiecing Together the Regulatory Circuitry of the Brain with Single Cell RNA Sequencing
Episode#133 – Manolis Kellis: Biology of Disease
PodcastLex Fridman Podcast
The field of computational biology uses the whole genome to design experiments that can only be interpreted in the context of the whole genome.
2:15:11 - 2:15:56 (00:45)
Summary
The field of computational biology uses the whole genome to design experiments that can only be interpreted in the context of the whole genome. Interdisciplinary teams are needed to combine the computer scientist way of thinking with the biological focus.