Chapter
Revolutionary Genetic Manipulation Technologies
2:15:56 - 2:23:31 (07:34)
The latest genetic manipulation technologies are combining with advanced analytics to create new ways of studying and intervening in disease at the level of individual cells, thereby allowing the exploration of combinatorial interventions to create synthetic biology constructs. Possible therapeutic applications include engineering circuits using microRNA sensors to detect the environment, such as tumor cells, immune cells, or stromal cells, and turn on particular interventions.
Clips
The use of high throughput perturbation technologies will allow genetic research to advance from the epigenomics to the cognitive level.
2:15:56 - 2:20:10 (04:13)
Summary
The use of high throughput perturbation technologies will allow genetic research to advance from the epigenomics to the cognitive level. This will result in a significant change to the way human biology is manipulated in the future.
ChapterRevolutionary Genetic Manipulation Technologies
Episode#133 – Manolis Kellis: Biology of Disease
PodcastLex Fridman Podcast
Synthetic biology constructs with cell-type identifiers can provide combinatorial interventions in different cells.
2:20:10 - 2:23:31 (03:21)
Summary
Synthetic biology constructs with cell-type identifiers can provide combinatorial interventions in different cells. This technology can lead to customized therapeutics for different organs or pathways, and researchers are exploring its potential in the fields of schizophrenia and cancer.