Chapter
Strategies for a Cheat Meal and the Metabolic Advantages of Ketogenic Diet
42:32 - 52:27 (09:55)
Dr. Rhonda Patrick discusses strategies for a controlled cheat meal and the metabolic advantages of ketogenic diet. She suggests adding fats and cap off the total calorie count of a cheat meal to avoid excess carb intake that could lead to a hypoglycemic effect. On the topic of ketogenic diet, she highlights how sustained nutritional ketosis enhances metabolic efficiency and suppresses appetite to naturally consume fewer calories.
Clips
Dr. Rhonda Patrick advises people doing nutritional ketosis to opt for a slow carb approach and consume sufficient amounts of fats to get a better hormonal response and restore glycogen levels when doing a cheat meal.
42:32 - 45:33 (03:01)
Summary
Dr. Rhonda Patrick advises people doing nutritional ketosis to opt for a slow carb approach and consume sufficient amounts of fats to get a better hormonal response and restore glycogen levels when doing a cheat meal. She suggests capping the calorie intake at a calculated level of around 400 grams of carbohydrates, and advises people to control their cravings by having soup before starting to eat.
ChapterStrategies for a Cheat Meal and the Metabolic Advantages of Ketogenic Diet
Episode#188: Dom D'Agostino on Disease Prevention, Cancer, and Living Longer
PodcastThe Tim Ferriss Show
Dom D'Agostino highlights the appetite suppressing effect of a ketogenic diet and the absence of postprandial blood glucose excursions that trigger cravings.
45:33 - 48:53 (03:19)
Summary
Dom D'Agostino highlights the appetite suppressing effect of a ketogenic diet and the absence of postprandial blood glucose excursions that trigger cravings. He also addresses the claim of no metabolic advantage from a ketogenic diet and acknowledges the need for more emerging data.
ChapterStrategies for a Cheat Meal and the Metabolic Advantages of Ketogenic Diet
Episode#188: Dom D'Agostino on Disease Prevention, Cancer, and Living Longer
PodcastThe Tim Ferriss Show
Metformin appears to have a calorie restriction mimetic effect, which can lead to lower blood glucose levels and an elevation of ketones.
48:53 - 52:27 (03:33)
Summary
Metformin appears to have a calorie restriction mimetic effect, which can lead to lower blood glucose levels and an elevation of ketones. Ongoing studies, such as the MILE study, are investigating metformin's potential in reversing gene expression in older adults with impaired glucose tolerance to that of young healthy subjects.