Chapter
The Complexity of Human Disease and Genetics
05:29 - 16:30 (11:00)
The complexity of human disease is comparable to that of the human genome and brain, as understanding one leads to a deeper understanding of the others, along with immune system function and cancer. The use of model organisms, combined with epidemiology, aids in the study of disease.
Clips
The speaker mentions talking to David Goggins and investing in quality temperature-controlled sleep to be comfortable while existing with one's demons.
05:29 - 08:22 (02:52)
Summary
The speaker mentions talking to David Goggins and investing in quality temperature-controlled sleep to be comfortable while existing with one's demons. An ad for a PodPro mattress by 8Sleep is included.
ChapterThe Complexity of Human Disease and Genetics
Episode#133 – Manolis Kellis: Biology of Disease
PodcastLex Fridman Podcast
Human genetics has now started driving basic biology as it helps in understanding the complexity of various diseases along with genome, epigenome, brain circuitry, immune system, and cancer complexity which further paves the way towards the progressive biological layers to understand human phylogenetically.
08:22 - 10:24 (02:02)
Summary
Human genetics has now started driving basic biology as it helps in understanding the complexity of various diseases along with genome, epigenome, brain circuitry, immune system, and cancer complexity which further paves the way towards the progressive biological layers to understand human phylogenetically.
ChapterThe Complexity of Human Disease and Genetics
Episode#133 – Manolis Kellis: Biology of Disease
PodcastLex Fridman Podcast
Understanding the relationship between diseases and their genetic components is crucial in the field of epidemiology, as it allows for a better understanding of the underlying mechanisms of these diseases.
10:24 - 12:49 (02:24)
Summary
Understanding the relationship between diseases and their genetic components is crucial in the field of epidemiology, as it allows for a better understanding of the underlying mechanisms of these diseases. By perturbing genes in mice, researchers can observe the effects on phenotype, helping to identify potential treatments for the disease.
ChapterThe Complexity of Human Disease and Genetics
Episode#133 – Manolis Kellis: Biology of Disease
PodcastLex Fridman Podcast
In this episode, the speaker discusses the importance of natural genetic variation in human experiments, which has been happening for thousands of years, highlighting how every person on the planet is a result of millions of experiments.
12:49 - 16:30 (03:40)
Summary
In this episode, the speaker discusses the importance of natural genetic variation in human experiments, which has been happening for thousands of years, highlighting how every person on the planet is a result of millions of experiments.