Chapter
The CRISPR System and Bacteria Immunity
1:33:25 - 1:38:07 (04:41)
Bacteria remember and defend themselves against viruses through a clustered repeat interspersed mechanism known as the CRISPR system that uses guide RNAs to scan the genome and cut any viruses that match with it.
Clips
Bacteria use the CRISPR system to remember defeated viruses by saving a part of it in their genomes which can later be used to cut the genome of the virus during future attacks, and the DNA repair mechanism fixes the genome by using these homologous regions.
1:33:25 - 1:36:59 (03:33)
CRISPR
Summary
Bacteria use the CRISPR system to remember defeated viruses by saving a part of it in their genomes which can later be used to cut the genome of the virus during future attacks, and the DNA repair mechanism fixes the genome by using these homologous regions.
ChapterThe CRISPR System and Bacteria Immunity
Episode#133 – Manolis Kellis: Biology of Disease
PodcastLex Fridman Podcast
Homologous based repair is a mechanism utilized in genome editing and CRISPR to co-opt the fixing of damaged DNA segments by using homologous segments to repair them.
1:36:59 - 1:38:07 (01:08)
CRISPR
Summary
Homologous based repair is a mechanism utilized in genome editing and CRISPR to co-opt the fixing of damaged DNA segments by using homologous segments to repair them. Prime editing is a newer generation of CRISPR that has been making headlines.