Chapter
The Effects of Nutritional Ketosis on Apolipoprotein E4 Expression
33:05 - 42:32 (09:26)
Nutritional ketosis and intermittent fasting can have favorable metabolic and signaling effects for those with Apolipoprotein E4 (APO E4) gene. A study by Sam Henderson showed that APO E4 positive patients did not respond as well to medium chain triglyceride (MCT) oil based supplements, so actual carbohydrate restriction associated with nutritional ketosis may be more beneficial.
Clips
The effects of a ketogenic diet on apo E4 carriers varies, with some studies showing less response to medium chain triglyceride supplementation in regards to cognitive performance for patients that are apo E4 positive.
33:05 - 38:53 (05:48)
Summary
The effects of a ketogenic diet on apo E4 carriers varies, with some studies showing less response to medium chain triglyceride supplementation in regards to cognitive performance for patients that are apo E4 positive. However, nutritional ketosis and intermittent fasting have shown to activate pathways that are downregulated by apo E4, making them favorable to those with it.
ChapterThe Effects of Nutritional Ketosis on Apolipoprotein E4 Expression
Episode#188: Dom D'Agostino on Disease Prevention, Cancer, and Living Longer
PodcastThe Tim Ferriss Show
The speaker presents his experience in managing a brain tumor through a ketogenic diet and supplements.
38:53 - 42:32 (03:38)
Summary
The speaker presents his experience in managing a brain tumor through a ketogenic diet and supplements. He also shares advice for individuals with the apoE4 gene and discusses the impact of cheat meals on ketosis.